⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25656362 | 0.88 | BACE1 (0.41) | — | |
| SCHEMBL25656364 | 0.88 | BACE1 (0.41) | — | |
| SCHEMBL24403330 | 0.86 | BACE1 (0.41) | — | |
| SCHEMBL24403208 | 0.86 | BACE1 (0.41) | — | |
| Hydrochloric Acid SCHEMBL30631305 | 0.85 | BACE1 (0.41) | — | |
| Hydrochloric Acid SCHEMBL30631308 | 0.85 | BACE1 (0.41) | — | |
| SCHEMBL26312560 | 0.85 | — | — | |
| SCHEMBL24447558 | 0.84 | BACE1 (0.39) | — | |
| SCHEMBL24447982 | 0.84 | BACE1 (0.39) | — | |
| SCHEMBL27034725 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230295175-A1 | PROCESSES FOR THE PREPARATION OF SUBSTITUTED SPIROOXINDOLE DERIVATIVES | ENANTA PHARMACEUTICALS, INC. | 2023-09-21 | — | — | US | disclosed |