Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 20/20 | 0.46 |
| ▸ | PARP2 | Q9UGN5 | 6/20 | 0.46 |
| ▸ | PARP6 | Q2NL67 | 4/20 | 0.43 |
| ▸ | PARP3 | Q9Y6F1 | 4/20 | 0.43 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | TNKS | O95271 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26313892 | 1.00 | PARP1 (0.46) | PARP1PARP2PARP6PARP3TIPARP | |
| SCHEMBL26309204 | 1.00 | PARP1 (0.46) | PARP1PARP2PARP6PARP3TIPARP | |
| SCHEMBL26309191 | 0.89 | PARP1 (0.57) | PARP1PARP2PARP6PARP3TIPARP | |
| SCHEMBL26313739 | 0.89 | PARP1 (0.57) | PARP1PARP2PARP6PARP3TIPARP | |
| SCHEMBL26313737 | 0.89 | PARP1 (0.57) | PARP1PARP2PARP6PARP3TIPARP | |
| SCHEMBL26309209 | 0.88 | PARP1 (0.39) | PARP1PARP2PARP6PARP3KCNH2 | |
| SCHEMBL26313898 | 0.88 | PARP1 (0.39) | PARP1PARP2PARP6PARP3KCNH2 | |
| SCHEMBL26309198 | 0.87 | PARP1 (0.49) | PARP1PARP2PARP6PARP3TIPARP | |
| SCHEMBL26313750 | 0.87 | PARP1 (0.49) | PARP1PARP2PARP6PARP3TIPARP | |
| SCHEMBL26313754 | 0.87 | PARP1 (0.49) | PARP1PARP2PARP6PARP3TIPARP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023178035-A1 | MULTICYCLIC COMPOUNDS | SLAP PHARMACEUTICALS LLC (US) | 2023-09-21 | — | — | WO | disclosed |