⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL873762 | 0.71 | — | — | |
| SCHEMBL19204323 | 0.71 | — | — | |
| SCHEMBL10083426 | 0.68 | — | — | |
| SCHEMBL25599345 | 0.68 | — | — | |
| SCHEMBL21728057 | 0.65 | — | — | |
| SCHEMBL24894481 | 0.65 | — | — | |
| SCHEMBL26322053 | 0.65 | — | — | |
| SCHEMBL10158553 | 0.63 | — | — | |
| SCHEMBL2772672 | 0.62 | — | — | |
| SCHEMBL22851435 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8163919-B2 | Imidazopyridinyl benzamide mitotic kinesin inhibitors | CYTOKINETICS, INCORPORATED (US) | 2012-04-24 | — | — | US | disclosed |
| US-20090306127-A1 | Certain Chemical Entities, Compositions and Methods | CYTOKINETICS, INC | 2009-12-10 | — | — | US | disclosed |