SCHEMBL26314441

SCHEMBL26314441

c1ccc(Nc2sc3ccccc3c2Nc2ccccc2)cc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 7/20 0.66
TDO2 P48775 2/20 0.46
KDM1A O60341 2/20 0.46
EPAS1 Q99814 1/20 0.44
GPR3 P46089 1/20 0.43
HSD17B10 Q99714 3/20 0.41
KMT2A Q03164 3/20 0.41
MEN1 O00255 2/20 0.41
MAPT P10636 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
KDM4E B2RXH2 1/20 0.41
GLA P06280 1/20 0.41
GAA P10253 1/20 0.41
RECQL P46063 1/20 0.41
NPC1 O15118 1/20 0.41
CASP3 P42574 1/20 0.41
RAB9A P51151 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
SENP8 Q96LD8 1/20 0.41
SENP7 Q9BQF6 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26314448 0.87 IDO1 (0.60) IDO1TDO2KDM1AEPAS1GPR3
SCHEMBL15447095 0.79 IDO1 (1.00) IDO1TDO2KDM1AEPAS1GPR3
SCHEMBL11561685 0.78 IDO1 (0.62) IDO1TDO2KDM1AEPAS1GPR3
SCHEMBL26314445 0.76 IDO1 (0.48) IDO1TDO2KDM1AEPAS1GPR3
SCHEMBL15443296 0.73 IDO1 (0.55) IDO1TDO2KDM1AKMT2AMEN1
SCHEMBL23514221 0.72 IDO1 (0.62) IDO1TDO2KDM1AEPAS1HSD17B10
SCHEMBL1922099 0.71 KDM1A (0.70) IDO1KDM1AHSD17B10KMT2AMEN1
SCHEMBL29601561 0.71 KDM1A (0.70) IDO1KDM1AHSD17B10KMT2AMEN1
SCHEMBL7601536 0.69 KDM1A (0.60) IDO1KDM1AHSD17B10KMT2AMEN1
SCHEMBL22505879 0.69 IDO1 (0.51) IDO1TDO2KDM1AEPAS1GPR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230263058-A1 ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT CANON KABUSHIKI KAISHA (JP) 2023-08-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230263058-A1 ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT NR2E3, LGR4, NCOA4 IDO1 2191/4885TDO2 939/4885KDM1A 1796/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.