Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 20/20 | 0.52 |
| ▸ | PARP2 | Q9UGN5 | 12/20 | 0.52 |
| ▸ | PARP6 | Q2NL67 | 9/20 | 0.52 |
| ▸ | PARP3 | Q9Y6F1 | 8/20 | 0.52 |
| ▸ | TNKS | O95271 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26309932 | 1.00 | PARP1 (0.52) | PARP1PARP2PARP6PARP3TNKS | |
| SCHEMBL26309931 | 0.93 | PARP1 (0.55) | PARP1PARP2PARP6PARP3TNKS | |
| SCHEMBL26314628 | 0.93 | PARP1 (0.55) | PARP1PARP2PARP6PARP3TNKS | |
| SCHEMBL26314627 | 0.93 | PARP1 (0.55) | PARP1PARP2PARP6PARP3TNKS | |
| SCHEMBL26314609 | 0.89 | PARP1 (0.54) | PARP1PARP2PARP6PARP3TNKS | |
| SCHEMBL26309835 | 0.89 | PARP1 (0.54) | PARP1PARP2PARP6PARP3TNKS | |
| SCHEMBL26314611 | 0.89 | PARP1 (0.54) | PARP1PARP2PARP6PARP3TNKS | |
| SCHEMBL26314616 | 0.88 | PARP1 (0.54) | PARP1PARP2PARP6PARP3TNKS | |
| SCHEMBL26314618 | 0.88 | PARP1 (0.54) | PARP1PARP2PARP6PARP3TNKS | |
| SCHEMBL26309840 | 0.88 | PARP1 (0.54) | PARP1PARP2PARP6PARP3TNKS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023178035-A1 | MULTICYCLIC COMPOUNDS | SLAP PHARMACEUTICALS LLC (US) | 2023-09-21 | — | — | WO | disclosed |