Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 19/20 | 0.44 |
| ▸ | PARP2 | Q9UGN5 | 11/20 | 0.44 |
| ▸ | PARP6 | Q2NL67 | 9/20 | 0.39 |
| ▸ | PARP3 | Q9Y6F1 | 8/20 | 0.39 |
| ▸ | TNKS | O95271 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | HTR1D | P28221 | 1/20 | 0.37 |
| ▸ | HTR1B | P28222 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26314915 | 1.00 | PARP1 (0.44) | PARP1PARP2PARP6PARP3TNKS | |
| SCHEMBL26310081 | 1.00 | PARP1 (0.44) | PARP1PARP2PARP6PARP3TNKS | |
| SCHEMBL26314910 | 0.93 | PARP1 (0.44) | PARP1PARP2PARP6PARP3TNKS | |
| SCHEMBL26310080 | 0.93 | PARP1 (0.44) | PARP1PARP2PARP6PARP3TNKS | |
| SCHEMBL26314912 | 0.93 | PARP1 (0.44) | PARP1PARP2PARP6PARP3TNKS | |
| SCHEMBL26309945 | 0.89 | PARP1 (0.44) | PARP1PARP2PARP6PARP3TNKS | |
| SCHEMBL26314900 | 0.89 | PARP1 (0.44) | PARP1PARP2PARP6PARP3TNKS | |
| SCHEMBL26309840 | 0.88 | PARP1 (0.54) | PARP1PARP2PARP6PARP3TNKS | |
| SCHEMBL26314618 | 0.88 | PARP1 (0.54) | PARP1PARP2PARP6PARP3TNKS | |
| SCHEMBL26314616 | 0.88 | PARP1 (0.54) | PARP1PARP2PARP6PARP3TNKS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023178035-A1 | MULTICYCLIC COMPOUNDS | SLAP PHARMACEUTICALS LLC (US) | 2023-09-21 | — | — | WO | disclosed |