Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.45 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.45 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 11/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 7/20 | 0.43 |
| ▸ | S1PR5 | Q9H228 | 5/20 | 0.43 |
| ▸ | TPH1 | P17752 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2631511 | 0.89 | S1PR1 (0.49) | S1PR1S1PR3S1PR5TPH1 | |
| SCHEMBL2631498 | 0.89 | S1PR1 (0.49) | MAP4K4PRKCDMINK1S1PR1S1PR3 | |
| SCHEMBL2631495 | 0.89 | S1PR1 (0.49) | S1PR1S1PR3S1PR5 | |
| SCHEMBL2130705 | 0.87 | S1PR1 (0.55) | S1PR1S1PR3S1PR5 | |
| SCHEMBL2631510 | 0.87 | S1PR1 (0.49) | MAP4K4PRKCDMINK1S1PR1S1PR3 | |
| SCHEMBL2619453 | 0.84 | S1PR1 (0.44) | MAP4K4PRKCDMINK1KDM4EHSD17B10 | |
| SCHEMBL2135247 | 0.84 | S1PR1 (0.56) | S1PR1S1PR3S1PR5 | |
| SCHEMBL2134091 | 0.81 | S1PR1 (0.62) | MAP4K4PRKCDMINK1S1PR1S1PR3 | |
| SCHEMBL2135228 | 0.80 | S1PR1 (0.55) | MAP4K4PRKCDMINK1S1PR1S1PR3 | |
| SCHEMBL2605697 | 0.79 | S1PR1 (0.65) | S1PR1S1PR3S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120101136-A1 | 5-MEMBERED HETEROARYL DERIVATIVES USED AS SPHINGOSINE 1- PHOSPHATE RECEPTOR AGONISTS | GLAXO GROUP LIMITED | 2012-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120101136-A1 | 5-MEMBERED HETEROARYL DERIVATIVES USED AS SPHINGOSINE 1- PHOSPHATE RECEPTOR AGONISTS | S1PR1, S1PR5, S1PR3 | BCHE 4460/4885ACHE 4737/4885MAP4K4 1653/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.