SCHEMBL2631640

SCHEMBL2631640

Cc1cc(C(C)C)c(O)c(-n2nc3ccccc3n2)c1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 7/20 0.64
RAB9A P51151 7/20 0.64
POLB P06746 2/20 0.57
LMNA P02545 3/20 0.56
KDM4E B2RXH2 4/20 0.47
ALDH1A1 P00352 5/20 0.45
SMN1; SMN2 Q16637 4/20 0.45
HPGD P15428 4/20 0.41
MAPT P10636 4/20 0.41
TDP1 Q9NUW8 2/20 0.41
NPSR1 Q6W5P4 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
GABRA1 P14867 3/20 0.36
GABRB1 P18505 2/20 0.36
CA1 P00915 2/20 0.35
CA2 P00918 2/20 0.35
CYP1A2 P05177 2/20 0.35
SLC6A2 P23975 2/20 0.35
HTR2B P41595 2/20 0.35
GABRB2 P47870 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3381678 0.87 NPC1 (0.59) NPC1RAB9APOLBLMNAKDM4E
SCHEMBL29364518 0.87 NPC1 (0.59) NPC1RAB9APOLBLMNAKDM4E
SCHEMBL4357048 0.86 NPC1 (0.50) NPC1RAB9APOLBLMNAKDM4E
SCHEMBL9183011 0.86 NPC1 (0.58) NPC1RAB9APOLBLMNAKDM4E
SCHEMBL12852114 0.83 NPC1 (0.54) NPC1RAB9APOLBLMNAKDM4E
SCHEMBL20394036 0.83 NPC1 (0.54) NPC1RAB9APOLBLMNAKDM4E
SCHEMBL31252559 0.83 NPC1 (0.54) NPC1RAB9APOLBLMNAKDM4E
SCHEMBL10194930 0.83 NPC1 (0.54) NPC1RAB9APOLBLMNAKDM4E
SCHEMBL28539118 0.82 NPC1 (0.44) NPC1RAB9APOLBLMNAKDM4E
SCHEMBL26658049 0.81 NPC1 (0.46) NPC1RAB9APOLBLMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240110120-A1 METHOD FOR MAKING BASE OIL WITH ENHANCED COLOR STABILITY CHEVRON U.S.A. INC. (US) 2024-04-04 US claimed
EP-4281528-A1 METHOD FOR MAKING BASE OIL WITH ENHANCED COLOR STABILITY Chevron U.S.A. Inc. (US) 2023-11-29 EP claimed
US-20240110120-A1 METHOD FOR MAKING BASE OIL WITH ENHANCED COLOR STABILITY CHEVRON U.S.A. INC. (US) 2024-04-04 US disclosed
EP-4281528-A1 METHOD FOR MAKING BASE OIL WITH ENHANCED COLOR STABILITY Chevron U.S.A. Inc. (US) 2023-11-29 EP disclosed
WO-2014111566-A2 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A MEROCYANINE AND AN INSOLUBLE ORGANIC UV-SCREENING AGENT AND/OR AN INSOLUBLE INORGANIC UV- SCREENING AGENT L'OREAL (FR) 2014-07-24 WO disclosed
US-8221855-B2 Cellulose derivative film, optical compensation film, polarizing plate, and liquid crystal device FUJIFILM CORPORATION (JP) 2012-07-17 US disclosed
US-8159634-B2 Liquid crystal display device FUJIFILM CORPORATION (JP) 2012-04-17 US disclosed
US-20090161043-A1 LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2009-06-25 US disclosed
US-20090117294-A1 CELLULOSE DERIVATIVE FILM, OPTICAL COMPENSATION FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DEVICE FUJIFILM CORPORATION (JP) 2009-05-07 US disclosed