Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 19/20 | 0.45 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25401732 | 1.00 | KRAS (0.45) | KRASMAPK3MAPK1 | |
| SCHEMBL26598263 | 0.87 | KRAS (0.45) | KRASMAPK3MAPK1 | |
| SCHEMBL26118890 | 0.86 | KRAS (0.44) | KRASMAPK3MAPK1 | |
| SCHEMBL31242650 | 0.86 | KRAS (0.44) | KRASMAPK3MAPK1 | |
| SCHEMBL31123134 | 0.85 | KRAS (0.43) | KRASMAPK3MAPK1 | |
| SCHEMBL25402473 | 0.84 | KRAS (0.43) | KRASMAPK3MAPK1 | |
| SCHEMBL25402469 | 0.84 | KRAS (0.43) | KRASMAPK3MAPK1 | |
| SCHEMBL25402622 | 0.83 | KRAS (0.41) | KRAS | |
| SCHEMBL25402626 | 0.83 | KRAS (0.41) | KRAS | |
| SCHEMBL25402547 | 0.83 | KRAS (0.39) | KRASMAPK3MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023172737-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | KUMQUAT BIOSCIENCES INC. (US) | 2023-09-14 | — | — | WO | disclosed |