Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.39 |
| ▸ | CCNC | P24863 | 7/20 | 0.39 |
| ▸ | CDK8 | P49336 | 7/20 | 0.39 |
| ▸ | CDK19 | Q9BWU1 | 7/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 4/20 | 0.38 |
| ▸ | BRD4 | O60885 | 2/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.38 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.38 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25781396 | 0.80 | FGFR3 (0.44) | FAAHFGFR3CCNCCDK8CDK19 | |
| SCHEMBL25785311 | 0.80 | CDK2 (0.72) | CCNE1CDK2 | |
| SCHEMBL25784855 | 0.77 | CCNE1 (0.63) | CCNE1CDK2BRD4 | |
| SCHEMBL26320679 | 0.76 | BRD4 (0.49) | BRD4 | |
| SCHEMBL29769081 | 0.71 | PDE1C (0.48) | FAAHCREBBPBRD4PDE1CTRPA1 | |
| SCHEMBL25785187 | 0.69 | PDGFRB (0.47) | CCNE1CDK2BRD4 | |
| SCHEMBL15342448 | 0.68 | CDK2 (0.46) | CDK2PDE1C | |
| Hydrochloric Acid SCHEMBL30567988 | 0.67 | PDE1C (0.45) | PDE1C | |
| Hydrochloric Acid SCHEMBL21381782 | 0.67 | PDE1C (0.45) | PDE1C | |
| SCHEMBL1365601 | 0.67 | PDE1C (0.44) | FAAHCREBBPBRD4PDE1CTRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023168686-A1 | SUBSTITUTED CYCLOPENTANES AS CDK2 INHIBITORS | QILU REGOR THERAPEUTICS INC. (CN) | 2023-09-14 | — | — | WO | disclosed |