Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.33 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30180668 | 0.94 | SYK (0.39) | MAPTSYKFGFR1FGFR2FGFR3 | |
| SCHEMBL23999550 | 0.94 | SYK (0.39) | MAPTSYKFGFR1FGFR2FGFR3 | |
| SCHEMBL26323160 | 0.92 | MAPT (0.39) | MAPTSYKKDRPOLBSMN1; SMN2 | |
| SCHEMBL26323217 | 0.89 | MAPT (0.40) | MAPTPOLBSMN1; SMN2TSHRMAPK1 | |
| SCHEMBL26323193 | 0.89 | MAPT (0.40) | MAPTPOLBSMN1; SMN2TSHRMAPK1 | |
| SCHEMBL24003965 | 0.89 | PDPK1 (0.41) | MAPTSYKPOLBSMN1; SMN2TSHR | |
| SCHEMBL23999752 | 0.89 | PDPK1 (0.41) | MAPTSYKPOLBSMN1; SMN2TSHR | |
| SCHEMBL30180421 | 0.89 | PDPK1 (0.41) | MAPTSYKPOLBSMN1; SMN2TSHR | |
| SCHEMBL23999947 | 0.89 | PDPK1 (0.41) | MAPTSYKPOLBSMN1; SMN2TSHR | |
| SCHEMBL23999351 | 0.88 | MAPT (0.35) | MAPTSYKPOLBSMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230295114-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230295114-A1 | AKT3 MODULATORS | AKT3, AKT2, MTOR | MAPT 3962/4885SYK 1989/4885FGFR1 1349/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.