Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 14/20 | 0.63 |
| ▸ | MAPKAPK2 | P49137 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | MET | P08581 | 1/20 | 0.46 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30180360 | 0.88 | KDR (0.63) | KDRMAPKAPK2MET | |
| SCHEMBL23999699 | 0.88 | KDR (0.63) | KDRMAPKAPK2MET | |
| SCHEMBL30210280 | 0.88 | KDR (0.63) | KDRMAPKAPK2MET | |
| SCHEMBL23999511 | 0.88 | KDR (0.63) | KDRMAPKAPK2MET | |
| SCHEMBL23999513 | 0.85 | MAPKAPK2 (0.52) | KDRMAPKAPK2 | |
| SCHEMBL25455011 | 0.85 | KDR (0.71) | KDRNPC1RAB9AMET | |
| SCHEMBL23999449 | 0.85 | MAPKAPK2 (0.52) | KDRMAPKAPK2 | |
| SCHEMBL30180457 | 0.84 | KDR (0.56) | KDRMAPKAPK2MET | |
| SCHEMBL23999898 | 0.84 | KDR (0.56) | KDRMAPKAPK2MET | |
| SCHEMBL23999677 | 0.83 | KDR (0.55) | KDRMAPKAPK2NPC1RAB9AMET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230295114-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230295114-A1 | AKT3 MODULATORS | AKT3, AKT2, MTOR | KDR 3433/4885MAPKAPK2 151/4885NPC1 1106/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.