Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 9/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.67 |
| ▸ | RXRA | P19793 | 1/20 | 0.67 |
| ▸ | MPC2 | O95563 | 1/20 | 0.45 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | KDM4A | O75164 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13743064 | 1.00 | PPARG (0.69) | PPARGCYP3A4RXRAMPC2CYP2C8 | |
| Hydrochloric Acid SCHEMBL1162242 | 0.99 | PPARG (0.69) | PPARGCYP3A4RXRAMPC2CYP2C8 | |
| SCHEMBL26040553 | 0.86 | PPARG (0.61) | PPARGCYP3A4RXRAMPC2CYP2C8 | |
| SCHEMBL25617592 | 0.86 | PPARG (0.54) | PPARGCYP3A4RXRAMPC2CYP2C8 | |
| SCHEMBL25617573 | 0.85 | PPARG (0.72) | PPARGCYP3A4RXRAMPC2CYP2C8 | |
| SCHEMBL20162392 | 0.85 | PPARG (0.72) | PPARGCYP3A4RXRAMPC2CYP2C8 | |
| SCHEMBL25617570 | 0.85 | PPARG (0.72) | PPARGCYP3A4RXRAMPC2CYP2C8 | |
| SCHEMBL20162394 | 0.85 | PPARG (0.72) | PPARGCYP3A4RXRAMPC2CYP2C8 | |
| SCHEMBL18021003 | 0.85 | PPARG (0.72) | PPARGCYP3A4RXRAMPC2CYP2C8 | |
| SCHEMBL25617577 | 0.85 | PPARG (0.72) | PPARGCYP3A4RXRAMPC2CYP2C8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11767317-B1 | Methods of synthesizing enantiopure deuterium-enriched pioglitazone | POXEL SA (FR) | 2023-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11767317-B1 | Methods of synthesizing enantiopure deuterium-enriched pioglitazone | PPARD, GLP1R, DPP4 | PPARG 7/4885CYP3A4 13/4885RXRA 29/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.