SCHEMBL26329943

SCHEMBL26329943

c1ccc(-n2c3ccccc3c3cc(-n4c5ccccc5c5c4ccc4c6ccccc6n(-c6ccc7ccccc7c6)c45)ccc32)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.46
ATM Q13315 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
F2 P00734 1/20 0.35
F10 P00742 1/20 0.35
PRSS1 P07477 1/20 0.35
HPGD P15428 1/20 0.34
JAK2 O60674 1/20 0.33
JAK3 P52333 1/20 0.33
PTPN1 P18031 1/20 0.33
ALDH1A1 P00352 3/20 0.32
POLB P06746 2/20 0.32
PMM2 O15305 1/20 0.32
MPI P34949 1/20 0.32
PHOSPHO1 Q8TCT1 1/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
TSHR P16473 2/20 0.32
SIGMAR1 Q99720 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23600652 1.00 KDM4E (0.46) KDM4EATML3MBTL1F2F10
SCHEMBL26809845 0.97 KDM4E (0.49) KDM4EATML3MBTL1F2F10
SCHEMBL23233714 0.97 KDM4E (0.49) KDM4EATML3MBTL1F2F10
SCHEMBL23204243 0.97 KDM4E (0.49) KDM4EATML3MBTL1F2F10
SCHEMBL23600650 0.95 KDM4E (0.46) KDM4EATML3MBTL1F2F10
SCHEMBL23600649 0.95 KDM4E (0.46) KDM4EATML3MBTL1F2F10
SCHEMBL26809815 0.95 KDM4E (0.51) KDM4EATML3MBTL1F2F10
SCHEMBL10027522 0.95 KDM4E (0.51) KDM4EATML3MBTL1F2F10
SCHEMBL19653026 0.94 KDM4E (0.43) KDM4EATML3MBTL1F2F10
SCHEMBL17759915 0.94 KDM4E (0.43) KDM4EATML3MBTL1F2F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11723269-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-08-08 US disclosed
US-20230136708-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2023-05-04 US disclosed
US-20230136708-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2023-05-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11723269-B2 Organic electroluminescent materials and devices PUF60, CD99, DDT KDM4E 3163/4885ATM 3362/4885L3MBTL1 1292/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.