Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 16/20 | 0.72 |
| ▸ | PSMB2 | P49721 | 12/20 | 0.72 |
| ▸ | PSMB1 | P20618 | 11/20 | 0.72 |
| ▸ | PSMB8 | P28062 | 11/20 | 0.72 |
| ▸ | PSMB10 | P40306 | 11/20 | 0.72 |
| ▸ | PSMB11 | A5LHX3 | 10/20 | 0.72 |
| ▸ | PSMA7 | O14818 | 10/20 | 0.72 |
| ▸ | PSMA1 | P25786 | 10/20 | 0.72 |
| ▸ | PSMA2 | P25787 | 10/20 | 0.72 |
| ▸ | PSMA3 | P25788 | 10/20 | 0.72 |
| ▸ | PSMA4 | P25789 | 10/20 | 0.72 |
| ▸ | PSMB9 | P28065 | 10/20 | 0.72 |
| ▸ | PSMA5 | P28066 | 10/20 | 0.72 |
| ▸ | PSMB4 | P28070 | 10/20 | 0.72 |
| ▸ | PSMB6 | P28072 | 10/20 | 0.72 |
| ▸ | PSMB3 | P49720 | 10/20 | 0.72 |
| ▸ | PSMA6 | P60900 | 10/20 | 0.72 |
| ▸ | PSMA8 | Q8TAA3 | 10/20 | 0.72 |
| ▸ | PSMB7 | Q99436 | 10/20 | 0.72 |
| ▸ | PSMD11 | O00231 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18871668 | 1.00 | PSMB5 (0.72) | PSMB5PSMB2PSMB1PSMB8PSMB10 | |
| SCHEMBL84962 | 0.94 | PSMB5 (0.69) | PSMB5PSMB2PSMB1PSMB8PSMB10 | |
| SCHEMBL2633227 | 0.94 | PSMB5 (0.69) | PSMB5PSMB2PSMB1PSMB8PSMB10 | |
| SCHEMBL18871669 | 0.93 | PSMB5 (0.68) | PSMB5PSMB2PSMB1PSMB8PSMB10 | |
| SCHEMBL2633220 | 0.93 | PSMB5 (0.68) | PSMB5PSMB2PSMB1PSMB8PSMB10 | |
| SCHEMBL2633334 | 0.93 | PSMB5 (0.68) | PSMB5PSMB2PSMB1PSMB8PSMB10 | |
| SCHEMBL8282512 | 0.92 | PSMB5 (0.70) | PSMB5PSMB2PSMB1PSMB8PSMB10 | |
| SCHEMBL18871924 | 0.92 | PSMB5 (0.70) | PSMB5PSMB2PSMB1PSMB8PSMB10 | |
| SCHEMBL85003 | 0.90 | PSMB5 (0.58) | PSMB5PSMB2PSMB1PSMB8PSMB10 | |
| SCHEMBL2632873 | 0.89 | PSMB5 (0.68) | PSMB5PSMB2PSMB1PSMB8PSMB10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170136085-A1 | TARGETED THERAPEUTICS | TVA (ABC), LLC | 2017-05-18 | — | — | US | disclosed |
| US-20120094928-A1 | COMPOUNDS FOR ENZYME INHIBITION | ONYX THERAPEUTICS, INC. (US) | 2012-04-19 | — | — | US | disclosed |
| WO-2005105827-A2 | COMPOUNDS FOR PROTEASOME ENZYME INHIBITION | PROTEOLIX, INC. (US) | 2005-11-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170136085-A1 | TARGETED THERAPEUTICS | HSP90B1, HSP90AB1, CDC37 | PSMB5 1248/4885PSMB2 1729/4885PSMB1 1251/4885 |
| US-20120094928-A1 | COMPOUNDS FOR ENZYME INHIBITION | ANPEP, DNPEP, CPN1 | PSMB5 24/4885PSMB2 14/4885PSMB1 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.