⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7488111 | 0.77 | — | — | |
| SCHEMBL4268223 | 0.77 | — | — | |
| SCHEMBL22833229 | 0.76 | — | — | |
| SCHEMBL6027836 | 0.76 | — | — | |
| SCHEMBL20024042 | 0.76 | USP2 (0.31) | — | |
| SCHEMBL253076 | 0.75 | — | — | |
| SCHEMBL25043310 | 0.74 | KDM4E (0.36) | — | |
| SCHEMBL4588217 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL28662790 | 0.73 | — | — | |
| Water SCHEMBL6682358 | 0.73 | APOBEC3G (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 102 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1663227-A2 | DIHYDROPYRIDINE COMPOUNDS FOR TREATING OR PREVENTING METABOLIC DISORDERS | Synta Pharmaceuticals Corporation (US) | 2006-06-07 | — | — | EP | claimed |
| WO-2005025507-A2 | DIHYDROPYRIDINE COMPOUNDS FOR TREATING OR PREVENTING METABOLIC DISORDERS | SYNTA PHAMACEUTICALS CORP. (US) | 2005-03-24 | — | — | WO | claimed |
| CN-1107842-A | Substituted 1-arylpyrazoles | BAYER AG (DE) | 1995-09-06 | — | — | CN | claimed |
| EP-0659745-A1 | Substituted 1-aryl pyrazoles | BAYER AG (DE) | 1995-06-28 | — | — | EP | claimed |
| EP-4739393-A1 | TETRAHYDROQUINAZOLINE DERIVATIVES AS SELECTIVE CYTOTOXIC AGENTS | Merck Sharp & Dohme LLC (US) | 2026-05-13 | — | — | EP | disclosed |
| EP-4712961-A2 | KRAS G12S AND G12C INHIBITORS | Mirati Therapeutics, Inc. (US) | 2026-03-25 | — | — | EP | disclosed |
| US-12570655-B2 | Cysteine covalent modifiers of AKT1 and uses thereof | TERREMOTO BIOSCIENCES, INC. (US) | 2026-03-10 | — | — | US | disclosed |
| WO-2025081045-A9 | CYSTEINE COVALENT MODIFIERS OF AKT1 AND USES THEREOF | TERREMOTO BIOSCIENCES, INC. (US) | 2025-12-26 | — | — | WO | disclosed |
| US-20250289819-A1 | CYSTEINE COVALENT MODIFIERS OF AKT1 AND USES THEREOF | TERREMOTO BIOSCIENCES, INC. | 2025-09-18 | — | — | US | disclosed |
| US-20250276966-A1 | Nitrogen-Linked Benzisoxazole Sulfonamide Derivatives | PFIZER (US) | 2025-09-04 | — | — | US | disclosed |
| WO-2025081045-A1 | CYSTEINE COVALENT MODIFIERS OF AKT1 AND USES THEREOF | TERREMOTO BIOSCIENCES, INC. (US) | 2025-04-17 | — | — | WO | disclosed |
| US-20250122183-A1 | Nitrogen-Linked Benzisoxazole Sulfonamide Derivatives | PFIZER (US) | 2025-04-17 | — | — | US | disclosed |
| EP-0659745-B1 | Substituted 1-aryl pyrazoles | BAYER CROPSCIENCE AG (DE) | 2005-07-27 | — | — | EP | disclosed |
| EP-1555257-A1 | PROCESS FOR PRODUCING AROMATIC NITRILE COMPOUND | IHARA CHEMICAL INDUSTRY Co., Ltd. (JP) | 2005-07-20 | — | — | EP | disclosed |
| EP-1293501-A1 | Substituted 1-aryl-pyrazoles and their use as pesticides | Bayer CropScience AG (DE) | 2003-03-19 | — | — | EP | disclosed |
| US-RE37495-E1 | Substituted 1-arylpyrazoles | BAYER AKTIENGESELLSCHAFT (DE) | 2002-01-01 | — | — | US | disclosed |
| CN-1061037-C | Substituted 1-arylpyrazoles | BAYER AG (DE) | 2001-01-24 | — | — | CN | disclosed |
| US-5580843-A | INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-12-03 | — | — | US | disclosed |
| CN-1107842-A | Substituted 1-arylpyrazoles | BAYER AG (DE) | 1995-09-06 | — | — | CN | disclosed |
| EP-0659745-A1 | Substituted 1-aryl pyrazoles | BAYER AG (DE) | 1995-06-28 | — | — | EP | disclosed |