Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNIK | Q9UKE5 | 20/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26337450 | 0.85 | TNIK (0.62) | TNIK | |
| SCHEMBL31203630 | 0.82 | TNIK (0.81) | TNIK | |
| SCHEMBL21259109 | 0.81 | TNIK (0.72) | TNIK | |
| SCHEMBL21247564 | 0.81 | TNIK (1.00) | TNIK | |
| SCHEMBL21259138 | 0.80 | TNIK (0.66) | TNIK | |
| SCHEMBL22978350 | 0.79 | TNIK (0.64) | TNIK | |
| SCHEMBL21247692 | 0.78 | TNIK (0.88) | TNIK | |
| SCHEMBL21247997 | 0.78 | TNIK (0.67) | TNIK | |
| SCHEMBL21262484 | 0.78 | TNIK (0.73) | TNIK | |
| SCHEMBL21262478 | 0.78 | TNIK (0.72) | TNIK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3749647-B1 | N-(5-(PHENYL)-1H-PYRAZOL-3-YL)-1H-INDOL-5-AMINE DERIVATIVES AS TNIK INHIBITORS FOR THE TREATMENT OF CANCER | KOREA RES INST CHEMICAL TECH (KR) | 2023-09-27 | — | — | EP | disclosed |