Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 3/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | EP300 | Q09472 | 1/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9308288 | 1.00 | — | — | |
| SCHEMBL28493769 | 1.00 | TSHR (0.48) | TSHRALDH1A1THRBFAAHTRPV1 | |
| SCHEMBL27564346 | 1.00 | TSHR (0.48) | TSHRALDH1A1THRBFAAHTRPV1 | |
| SCHEMBL6841419 | 0.97 | — | — | |
| SCHEMBL1165079 | 0.88 | — | — | |
| SCHEMBL25177176 | 0.82 | TSHR (0.58) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL25176521 | 0.82 | TSHR (0.58) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL25174145 | 0.82 | TSHR (0.58) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL25173853 | 0.82 | TSHR (0.58) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL25171005 | 0.82 | TSHR (0.58) | TSHRTHRBFAAHTRPV1DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230089867-A1 | CYCLIC PENTAMER COMPOUNDS AS PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (PCSK9) INHIBITORS FOR THE TREATMENT OF METABOLIC DISORDER | NOVARTIS AG (CH) | 2023-03-23 | — | — | US | disclosed |
| EP-3887363-A1 | CYCLIC PENTAMER COMPOUNDS AS PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (PCSK9) INHIBITORS FOR THE TREATMENT OF METABOLIC DISORDER | Novartis AG (CH) | 2021-10-06 | — | — | EP | disclosed |
| CN-109134716-B | Vanadium catalyst and method for preparing olefin polymer | 北京引发科技有限公司 | 2020-11-10 | — | — | CN | disclosed |
| WO-2020110008-A1 | CYCLIC PENTAMER COMPOUNDS AS PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (PCSK9) INHIBITORS FOR THE TREATMENT OF METABOLIC DISORDER | NOVARTIS AG (CH) | 2020-06-04 | — | — | WO | disclosed |
| CN-110114426-A | Antifouling paint compositions, antifouling coat, the substrate with antifouling coat and its manufacturing method and anti-fouling method | 中国涂料株式会社 | 2019-08-09 | — | — | CN | disclosed |
| CN-109906254-A | Antifouling coating composition, antifouling coating film, substrate with antifouling coating film, method for producing substrate with antifouling coating film, and antifouling method | 中国涂料株式会社 | 2019-06-18 | — | — | CN | disclosed |
| CN-109415595-A | Antifouling paint compositions, antifouling coat, the substrate with antifouling coat and its manufacturing method and anti-fouling method | 中国涂料株式会社 | 2019-03-01 | — | — | CN | disclosed |
| CN-109311284-A | Antifouling coat, antifouling substrate and ship is laminated | 中国涂料株式会社 | 2019-02-05 | — | — | CN | disclosed |
| CN-109196064-A | Antifouling coating composition, antifouling coating film, laminated antifouling coating film, substrate with antifouling coating film, method for producing same, and antifouling method | 中国涂料株式会社 | 2019-01-11 | — | — | CN | disclosed |
| CN-108603069-A | Antifouling paint compositions, film and the base material with film | 中国涂料株式会社 | 2018-09-28 | — | — | CN | disclosed |
| WO-2005075582-A1 | ANTIFOULING COATING COMPOSITION AND ITS USE ON MAN MADE STRUCTURES | AKZO NOBEL COATINGS INTERNATIONAL B.V. (NL) | 2005-08-18 | — | — | WO | disclosed |
| EP-1098659-A4 | LIBRARIES OF POLYHYDROXAMATES AND THEIR ANALOGS | METAPHORE INC (US) | 2004-11-24 | — | — | EP | disclosed |
| EP-1098659-A2 | LIBRARIES OF POLYHYDROXAMATES AND THEIR ANALOGS | Metaphore, Inc. (US) | 2001-05-16 | — | — | EP | disclosed |
| EP-1001787-A1 | LIVER PROTECTION OR TREATMENT AGENTS COMPRISING ASIATIC ACID DERIVATIVES AS THE ACTIVE COMPONENT | DONG KOOK PHARMACEUTICAL CO., LTD. (KR) | 2000-05-24 | — | — | EP | disclosed |
| WO-2000004868-A2 | LIBRARIES OF POLYHYDROXAMATES AND THEIR ANALOGS | METAPHORE, INC. (US) | 2000-02-03 | — | — | WO | disclosed |
| EP-0971873-A1 | ASIATIC ACID DERIVATIVES AND MEDICINES FOR TREATING WOUNDS, WHICH CONTAINS THE SAME | DONG KOOK PHARMACEUTICAL CO., LTD. (KR) | 2000-01-19 | — | — | EP | disclosed |
| EP-0959890-A1 | MEDICINES FOR TREATING DEMENTIA OR COGNITIVE DISORDER, WHICH COMPRISES ASIATIC ACID DERIVATIVES | DONG KOOK PHARMACEUTICAL CO., LTD. (KR) | 1999-12-01 | — | — | EP | disclosed |
| WO-1998037899-A1 | LIVER PROTECTION OR TREATMENT AGENTS COMPRISING ASIATIC ACID DERIVATIVES AS THE ACTIVE COMPONENT | DONG KOOK PHARMACEUTICAL CO., LTD. (KR) | 1998-09-03 | — | — | WO | disclosed |
| WO-1998023278-A1 | MEDICINES FOR TREATING DEMENTIA OR COGNITIVE DISORDER, WHICH COMPRISES ASIATIC ACID DERIVATIVES | DONG KOOK PHARMACEUTICAL CO., LTD. (KR) | 1998-06-04 | — | — | WO | disclosed |
| WO-1998023574-A1 | ASIATIC ACID DERIVATIVES AND MEDICINES FOR TREATING WOUNDS, WHICH CONTAINS THE SAME | DONG KOOK PHARMACEUTICAL CO., LTD. (KR) | 1998-06-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230089867-A1 | CYCLIC PENTAMER COMPOUNDS AS PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (PCSK9) INHIBITORS FOR THE TREATMENT OF METABOLIC DISORDER | PCSK9, PCSK7, PCSK6 | TSHR 622/4885ALDH1A1 4625/4885THRB 786/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.