Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 17/20 | 0.39 |
| ▸ | IDH1 | O75874 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.36 |
| ▸ | PDE9A | O76083 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31364128 | 1.00 | OGA (0.39) | OGAIDH1CYP3A4CYP2B6PDE9A | |
| SCHEMBL27142843 | 0.85 | CYP3A4 (0.40) | CYP3A4CYP2B6PDE9A | |
| SCHEMBL26344117 | 0.85 | CYP3A4 (0.40) | CYP3A4CYP2B6PDE9A | |
| SCHEMBL29588283 | 0.85 | CYP3A4 (0.40) | CYP3A4CYP2B6PDE9A | |
| SCHEMBL30459333 | 0.83 | CYP3A4 (0.39) | CYP3A4CYP2B6PDE9A | |
| SCHEMBL31364035 | 0.83 | CYP3A4 (0.39) | CYP3A4CYP2B6PDE9A | |
| SCHEMBL26344132 | 0.83 | CYP3A4 (0.39) | CYP3A4CYP2B6PDE9A | |
| SCHEMBL26344141 | 0.83 | PARP1 (0.40) | CYP3A4CYP2B6PDE9A | |
| SCHEMBL31363880 | 0.83 | PARP1 (0.40) | CYP3A4CYP2B6PDE9A | |
| SCHEMBL31207897 | 0.82 | IDH1 (0.34) | IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119638680-A | Triazine diketone derivative, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2025-03-18 | — | — | CN | disclosed |
| CN-119638681-A | Triazine diketone derivative, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2025-03-18 | — | — | CN | disclosed |
| CN-119638682-A | Triazine diketone derivative, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2025-03-18 | — | — | CN | disclosed |
| CN-116323598-B | Triazine diketone derivative, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2024-11-15 | — | — | CN | disclosed |
| EP-4249474-A1 | TRIAZINE DIONE DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF IN MEDICINE | Jiangsu Hengrui Pharmaceuticals Co., Ltd. (CN) | 2023-09-27 | — | — | EP | disclosed |
| CN-116323598-A | Triazine diketone derivative, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2023-06-23 | — | — | CN | disclosed |