Ethyne

Ethyne

SCHEMBL263444

C#C.[LiH]

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethyne SCHEMBL5311661 1.00
Ethyne SCHEMBL11857679 0.87
Ethyne SCHEMBL27793030 0.87
Ethyne SCHEMBL10836715 0.87
Ethyne SCHEMBL7510234 0.87
Ethyne SCHEMBL2639865 0.87
Ethyne SCHEMBL144006 0.82
Ethyne SCHEMBL4753041 0.82
Ethyne SCHEMBL428 0.82
Ethyne SCHEMBL27961050 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2313 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4673446-A1 FLOW CHEMISTRY PROCESS FOR PREPARING AZA-BICYCLIC HETEROARYL COMPOUNDS Actinogen Medical Limited (AU) 2026-01-07 EP claimed
WO-2024178474-A1 FLOW CHEMISTRY PROCESS FOR PREPARING AZA-BICYCLIC HETEROARYL COMPOUNDS Actinogen Medical Limited (AU) 2024-09-06 WO claimed
EP-3323505-B1 HYDROSILYLATION REACTION CATALYST UNIV KYUSHU NAT UNIV CORP (JP) 2024-07-17 EP claimed
CN-117534042-A Impurity removing method for difluoro sulfimide 万华化学集团股份有限公司 2024-02-09 CN claimed
EP-4274863-A2 PHOTOCHROMIC DYES AND POLYMERIC MATRIX FOR AN EFFICIENT DIMMING FILM Sony Group Corporation (JP) 2023-11-15 EP claimed
WO-2022148752-A9 PHOTOCHROMIC DYES AND POLYMERIC MATRIX FOR AN EFFICIENT DIMMING FILM Sony Group Corporation (JP) 2023-08-03 WO claimed
CN-115448969-A Refining method of desogestrel 上海格苓凯生物科技有限公司 2022-12-09 CN claimed
CN-115380020-A Short and efficient process for the preparation of (1R, 3R) -2,2-dimethyl-3- (Z) -prop-1-en-1-yl) cyclopropanecarboxylic acids and esters S·J·帕雷克 2022-11-22 CN claimed
CN-112299991-B Preparation method of (E, E, Z) -10,12, 14-hexadecatriene acetate, composition and lure 宁波纽康生物技术有限公司 2022-10-11 CN claimed
WO-2022148752-A2 PHOTOCHROMIC DYES AND POLYMERIC MATRIX FOR AN EFFICIENT DIMMING FILM Sony Group Corporation (JP) 2022-07-14 WO claimed
EP-0177933-B1 INTERMEDIATES FOR MAKING 16-PHENOXY AND 16-SUBSTITUTED PHENOXY-PROSTATRIENOIC ACID DERIVATIVES SYNTEX (U.S.A.) INC. (US) 1989-05-10 EP claimed
US-4719054-A Process for the production of 17α-ethynyl-17β-hydroxy-18-methyl-4,15-estradien-3-one, and novel 3,5-estradien-17-one starting compounds for this process SCHERING AKTIENGESELLSCHAFT (DE) 1988-01-12 US claimed
CN-86102560-A 17 α-ethynyl-17 beta-hydroxies-18-methyl-4, the preparation method of 15-estradiene-3-ketone 1987-01-21 CN claimed
EP-0189951-A1 New process for the preparation of certain steroids, especially intermediates for the preparation of proligestone and related compounds, and new intermediates formed in this process AKZO N.V. (NL) 1986-08-06 EP claimed
EP-0188010-A1 New process for the preparation of certain steroids, especially intermediates for the preparation of proligestone and related compounds, and new intermediates formed in this process GIST-BROCADES N.V. (NL) 1986-07-23 EP claimed
EP-0177933-A2 Intermediates for making 16-phenoxy and 16-substituted phenoxy-prostatrienoic acid derivatives SYNTEX (U.S.A.) INC. (US) 1986-04-16 EP claimed
US-4520207-A REACTING THE ADDITION PRODUCT OF A THIENYLPALLADIUM COMPLEX AND BICYCLIC OLEFIN WITH A LITHIUM ACETYLIDE IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 1985-05-28 US claimed
US-4351949-A Bicyclic prostaglandin analogs and method of synthesis IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 1982-09-28 US claimed
US-4181674-A 5-Endo-protected hydroxyl-bicyclo[2,2,1]-heptan-2-ones and process for preparing same ALLEN & HANBURYS LIMITED (GB) 1980-01-01 US claimed
US-4057543-A Process for the preparation of 17β-hydroxy-3-oxo-17α-pregn-4-ene-21-carboxylic acid γ-lactone G. D. SEARLE & CO. (US) 1977-11-08 US claimed