Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 7/20 | 0.49 |
| ▸ | HRH1 | P35367 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | METAP1 | P53582 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 5/20 | 0.39 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17120414 | 0.81 | MEN1 (0.51) | HTR2AMEN1CYP3A4CYP2D6KMT2A | |
| SCHEMBL17121746 | 0.81 | MEN1 (0.51) | HTR2AMEN1CYP3A4CYP2D6KMT2A | |
| SCHEMBL26201345 | 0.81 | MEN1 (0.51) | HTR2AMEN1CYP3A4CYP2D6KMT2A | |
| SCHEMBL19158572 | 0.78 | MEN1 (0.49) | HTR2AMEN1CYP3A4CYP2D6KMT2A | |
| SCHEMBL2264568 | 0.77 | MEN1 (0.51) | HTR2AMEN1CYP3A4CYP2D6KMT2A | |
| SCHEMBL29570896 | 0.77 | MEN1 (0.51) | HTR2AMEN1CYP3A4CYP2D6KMT2A | |
| SCHEMBL24469485 | 0.77 | MEN1 (0.47) | HTR2AHRH1MEN1CYP3A4CYP2D6 | |
| SCHEMBL23308861 | 0.77 | MEN1 (0.47) | HTR2AMEN1CYP3A4CYP2D6KMT2A | |
| SCHEMBL11846170 | 0.75 | MEN1 (0.46) | HTR2AMEN1CYP3A4CYP2D6KMT2A | |
| SCHEMBL29700481 | 0.75 | MEN1 (0.49) | HTR2AMEN1CYP3A4CYP2D6KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4249474-A1 | TRIAZINE DIONE DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF IN MEDICINE | Jiangsu Hengrui Pharmaceuticals Co., Ltd. (CN) | 2023-09-27 | — | — | EP | disclosed |