Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | THRB | P10828 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | NAMPT | P43490 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.48 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.48 |
| ▸ | GRM1 | Q13255 | 8/20 | 0.44 |
| ▸ | GRM4 | Q14833 | 5/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL353101 | 0.82 | KDM4E (0.62) | MAPTKDM4EALDH1A1THRBMEN1 | |
| SCHEMBL11908920 | 0.82 | KDM4E (0.62) | MAPTKDM4EALDH1A1THRBMEN1 | |
| SCHEMBL1902377 | 0.80 | MAPT (0.66) | MAPTKDM4EALDH1A1THRBMEN1 | |
| SCHEMBL26332896 | 0.80 | KDM4E (0.61) | MAPTKDM4EALDH1A1THRBMEN1 | |
| SCHEMBL28244480 | 0.77 | KDM4E (0.57) | MAPTKDM4EALDH1A1THRBMEN1 | |
| SCHEMBL13753326 | 0.77 | MAPT (0.72) | MAPTKDM4EALDH1A1THRBMEN1 | |
| SCHEMBL13753382 | 0.77 | KDM4E (0.57) | MAPTKDM4EALDH1A1THRBMEN1 | |
| SCHEMBL10417495 | 0.76 | KDM4E (0.55) | MAPTKDM4EALDH1A1THRBMEN1 | |
| SCHEMBL8629804 | 0.76 | KDM4E (0.56) | MAPTKDM4EALDH1A1THRBMEN1 | |
| SCHEMBL13753490 | 0.74 | KDM4E (0.54) | MAPTKDM4EALDH1A1THRBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4249480-A1 | DIPHENYLPYRAZOLE COMPOUND, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Northwest A&F University (CN) | 2023-09-27 | — | — | EP | disclosed |