Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 20/20 | 0.85 |
| ▸ | PTK2 | Q05397 | 20/20 | 0.85 |
| ▸ | JAK3 | P52333 | 16/20 | 0.85 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2634305 | 0.92 | JAK2 (1.00) | JAK2PTK2JAK3 | |
| SCHEMBL2634745 | 0.91 | JAK2 (1.00) | JAK2PTK2JAK3 | |
| SCHEMBL2634510 | 0.87 | JAK2 (1.00) | JAK2PTK2JAK3 | |
| SCHEMBL13058850 | 0.85 | JAK2 (0.80) | JAK2PTK2JAK3 | |
| SCHEMBL2634358 | 0.84 | JAK2 (1.00) | JAK2PTK2JAK3 | |
| SCHEMBL2635441 | 0.84 | JAK2 (1.00) | JAK2PTK2JAK3 | |
| SCHEMBL2635053 | 0.83 | JAK2 (1.00) | JAK2PTK2JAK3 | |
| SCHEMBL2634903 | 0.82 | JAK2 (1.00) | JAK2PTK2JAK3 | |
| SCHEMBL2640394 | 0.82 | JAK2 (1.00) | JAK2PTK2JAK3 | |
| SCHEMBL2634617 | 0.81 | JAK2 (1.00) | JAK2PTK2JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2438066-A2 | PREPARATION AND USES OF 1,2,4-TRIAZOLO [1,5a]PYRIDINE DERIVATIVES | Cephalon, Inc. (US) | 2012-04-11 | — | — | EP | disclosed |
| WO-2010141796-A2 | PREPARATION AND USES OF 1,2,4-TRIAZOLO [1,5a] PYRIDINE DERIVATIVES | CEPHALON, INC. (US) | 2010-12-09 | — | — | WO | disclosed |