Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 20/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26349199 | 0.91 | IRAK4 (0.56) | IRAK4 | |
| SCHEMBL24607170 | 0.90 | IRAK4 (0.55) | IRAK4 | |
| SCHEMBL22848796 | 0.90 | IRAK4 (0.59) | IRAK4 | |
| SCHEMBL26346880 | 0.90 | IRAK4 (0.57) | IRAK4 | |
| SCHEMBL22848870 | 0.89 | IRAK4 (0.60) | IRAK4 | |
| SCHEMBL22848836 | 0.88 | IRAK4 (0.55) | IRAK4 | |
| SCHEMBL26346842 | 0.87 | IRAK4 (0.53) | IRAK4 | |
| SCHEMBL26355634 | 0.87 | IRAK4 (0.53) | IRAK4 | |
| SCHEMBL22849584 | 0.87 | IRAK4 (0.53) | IRAK4 | |
| SCHEMBL26346974 | 0.86 | IRAK4 (0.55) | IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230303526-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2023-09-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230303526-A1 | IRAK DEGRADERS AND USES THEREOF | IRAK2, IRAK3, IRAK1 | IRAK4 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.