Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.51 |
| ▸ | NPBWR1 | P48145 | 3/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.46 |
| ▸ | SCD | O00767 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.42 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9915005 | 0.91 | HDAC6 (0.49) | HDAC6NPBWR1TRPV1SCDKCNH2 | |
| SCHEMBL26358087 | 0.88 | HDAC6 (0.60) | HDAC6NPBWR1TRPV1SCDKCNH2 | |
| SCHEMBL9058427 | 0.84 | HDAC6 (0.62) | HDAC6NPBWR1TRPV1SCDKCNH2 | |
| SCHEMBL22326618 | 0.83 | SCN10A (0.55) | HDAC6NPBWR1TRPV1SCDKCNH2 | |
| SCHEMBL12250679 | 0.80 | SCN10A (0.47) | HDAC6NPBWR1TRPV1SCDKCNH2 | |
| SCHEMBL20847981 | 0.80 | KCNH2 (0.50) | HDAC6NPBWR1SCDKCNH2DGAT1 | |
| SCHEMBL12250680 | 0.79 | HDAC6 (0.61) | HDAC6NPBWR1TRPV1SCDKCNH2 | |
| SCHEMBL13890377 | 0.78 | CYP3A4 (0.45) | HDAC6NPBWR1TRPV1SCDKCNH2 | |
| SCHEMBL18629758 | 0.77 | TRPV1 (0.63) | HDAC6NPBWR1TRPV1SCD | |
| SCHEMBL19292362 | 0.77 | HDAC6 (0.46) | HDAC6NPBWR1TRPV1SCDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11777124-B2 | Proton-conducting PBI membrane processing with enhanced performance and durability | UNIVERSITY OF SOUTH CAROLINA (US) | 2023-10-03 | — | — | US | disclosed |