Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | PREP | P48147 | 2/20 | 0.30 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25216428 | 1.00 | CHRM2 (0.38) | CHRM2CHRM1CHRM3KDM1ADDB1 | |
| SCHEMBL30977190 | 0.91 | CHRM2 (0.36) | CHRM2CHRM1CHRM3KDM1ADDB1 | |
| SCHEMBL30520676 | 0.91 | CHRM2 (0.36) | CHRM2CHRM1CHRM3KDM1ADDB1 | |
| SCHEMBL30392186 | 0.91 | CHRM2 (0.36) | CHRM2CHRM1CHRM3KDM1ADDB1 | |
| SCHEMBL25242987 | 0.89 | CHRM2 (0.36) | CHRM2CHRM1CHRM3KDM1ADDB1 | |
| SCHEMBL30977192 | 0.88 | CHRM2 (0.39) | CHRM2CHRM1CHRM3KDM1ADDB1 | |
| SCHEMBL30998687 | 0.88 | CHRM2 (0.39) | CHRM2CHRM1CHRM3KDM1ADDB1 | |
| SCHEMBL25257754 | 0.88 | CHRM2 (0.39) | CHRM2CHRM1CHRM3KDM1ADDB1 | |
| SCHEMBL30977195 | 0.88 | CHRM2 (0.39) | CHRM2CHRM1CHRM3KDM1ADDB1 | |
| SCHEMBL25413842 | 0.87 | CHRM2 (0.37) | CHRM2CHRM1CHRM3DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023173014-A1 | KRAS INHIBITORS AND THEIR USE | BLOSSOMHILL THERAPEUTICS, INC. (US) | 2023-09-14 | — | — | WO | disclosed |
| WO-2023173014-A1 | KRAS INHIBITORS AND THEIR USE | BLOSSOMHILL THERAPEUTICS, INC. (US) | 2023-09-14 | — | — | WO | disclosed |