Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 14/20 | 0.76 |
| ▸ | FAAH | O00519 | 9/20 | 0.76 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | CNR1 | P21554 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3374041 | 0.87 | CNR2 (0.59) | CNR2FAAHMEN1KMT2APKM | |
| SCHEMBL6085774 | 0.87 | CNR2 (1.00) | CNR2FAAHMEN1KMT2APKM | |
| SCHEMBL3374035 | 0.85 | CNR2 (0.57) | CNR2FAAHMEN1KMT2APKM | |
| SCHEMBL30848467 | 0.81 | CNR2 (0.89) | CNR2FAAHMEN1KMT2APKM | |
| SCHEMBL1876596 | 0.80 | GRM5 (0.55) | CNR2FAAHMEN1KMT2ACNR1 | |
| SCHEMBL15163044 | 0.77 | CNR2 (0.47) | CNR2FAAHMEN1KMT2ACNR1 | |
| SCHEMBL17416213 | 0.75 | CNR2 (1.00) | CNR2FAAHMEN1KMT2ACNR1 | |
| SCHEMBL2638344 | 0.74 | CNR2 (0.79) | CNR2FAAHMEN1KMT2APKM | |
| SCHEMBL31650667 | 0.74 | KAT6A (0.58) | PKMKDM4EHPGDHSD17B10 | |
| SCHEMBL22819931 | 0.74 | KDM4E (0.52) | CNR2FAAHCNR1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2011529057-A | — | — | 2011-12-01 | — | — | JP | claimed |
| WO-2010011570-A1 | ADAMANTYL DIAMIDE DERIVATIVES AND USES OF SAME | H. LUNDBECK A/S (DK) | 2010-01-28 | — | — | WO | claimed |