⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1430406 | 1.00 | — | — | |
| SCHEMBL25246733 | 1.00 | — | — | |
| Chloromethane SCHEMBL8972585 | 0.94 | TDP1 (0.58) | — | |
| Methylamine SCHEMBL27691440 | 0.94 | TDP1 (0.46) | — | |
| Dimethylformamide SCHEMBL27672372 | 0.92 | TSHR (0.47) | — | |
| Methacrylic Acid SCHEMBL27749358 | 0.85 | TDP1 (0.40) | — | |
| SCHEMBL29279310 | 0.83 | TDP1 (0.39) | — | |
| SCHEMBL28350896 | 0.83 | TDP1 (0.43) | — | |
| SCHEMBL22402953 | 0.79 | — | — | |
| SCHEMBL7345258 | 0.78 | TDP1 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 558 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12234234-B2 | Method for synthesizing 1,7-naphthyridine derivatives | CHENGDA PHARMACEUTICALS CO., LTD. (CN) | 2025-02-25 | — | — | US | claimed |
| US-20240376106-A1 | PROCESS OF PREPARING A PD-1/PD-L1 INHIBITOR | INCYTE CORPORATION | 2024-11-14 | — | — | US | claimed |
| CN-117603072-A | 2-difluoro acetyl-3-dimethylamino acrylic acid compound, and preparation method and application thereof | 安徽泓泽新材料科技有限公司 | 2024-02-27 | — | — | CN | claimed |
| US-11780836-B2 | Process of preparing a PD-1/PD-L1 inhibitor | INCYTE CORPORATION (US) | 2023-10-10 | — | — | US | claimed |
| US-20220235044-A1 | METHOD FOR SYNTHESIZING 1,7-NAPHTHYRIDINE DERIVATIVES | CHENGDA PHARMACEUTICALS CO LTD (CN) | 2022-07-28 | — | — | US | claimed |
| US-20220144830-A1 | PROCESS OF PREPARING A PD-1/PD-L1 INHIBITOR | INCYTE CORPORATION | 2022-05-12 | — | — | US | claimed |
| CN-111285973-A | Star-shaped cationic polymer flocculant and preparation method thereof | 爱森（中国）絮凝剂有限公司 | 2020-06-16 | — | — | CN | claimed |
| CN-109762540-A | Supermolecule plugging agent and preparation method thereof | 中国石油集团川庆钻探工程有限公司 | 2019-05-17 | — | — | CN | claimed |
| CN-109705829-A | Pressure-bearing leakage-stopping slurry and preparation method thereof | 中国石油集团川庆钻探工程有限公司 | 2019-05-03 | — | — | CN | claimed |
| US-10039775-B2 | Preparation method for antitumor drug AP26113 | SUZHOU MIRACPHARMA TECHNOLOGY CO., LTD. (CN) | 2018-08-07 | — | — | US | claimed |
| CN-1270599-A | Polymerization processes and products and uses of the products | ALLIED COLLOIDS LTD (GB) | 2000-10-18 | — | — | CN | claimed |
| EP-1021466-A1 | POLYMERISATION PROCESSES AND PRODUCTS AND USES OF THE PRODUCTS | Ciba Specialty Chemicals Water Treatments Limited (GB) | 2000-07-26 | — | — | EP | claimed |
| EP-0759039-B1 | ACRYLATE POLYMERIZATION PROCESSES | XEROX CORP (US) | 1999-12-29 | — | — | EP | claimed |
| WO-1999014246-A1 | POLYMERISATION PROCESSES AND PRODUCTS AND USES OF THE PRODUCTS | CIBA SPECIALTY CHEMICALS WATER TREATMENTS LIMITED (GB) | 1999-03-25 | — | — | WO | claimed |
| CN-1147820-A | Acrylate polymerization processes | XEROX CORP (US) | 1997-04-16 | — | — | CN | claimed |
| CN-1109877-A | One-pot process for the preparation of 3-quinolone carboxylic acid derivatives | BAYER AG (DE) | 1995-10-11 | — | — | CN | claimed |
| EP-0289823-A2 | High strength wet webs for the production of paper and process for producing paper making fiber webs having wet web strength | AMERICAN CYANAMID COMPANY (US) | 1988-11-09 | — | — | EP | claimed |
| US-4666617-A | ALKYLAMINO-ACRYLATE POLYMERS, FATTY ACID, ALKYL PHOSPHATES | NIPPON KOKAN KABUSHIKI KAISHA (JP) | 1987-05-19 | — | — | US | claimed |
| WO-1985003722-A1 | ARTICLE SUITABLE FOR WIPING SURFACES | UNILEVER PLC (GB) | 1985-08-29 | — | — | WO | claimed |
| EP-0153146-A1 | Article suitable for wiping surfaces | UNILEVER N.V. (NL) | 1985-08-28 | — | — | EP | claimed |