Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 8/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | FDPS | P14324 | 2/20 | 0.33 |
| ▸ | CASP2 | P42575 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15154746 | 1.00 | EPHX2 (0.44) | EPHX2CA2CA1EPHX1PPARA | |
| SCHEMBL25273674 | 1.00 | EPHX2 (0.44) | EPHX2CA2CA1EPHX1PPARA | |
| SCHEMBL15264198 | 1.00 | EPHX2 (0.44) | EPHX2CA2CA1EPHX1PPARA | |
| Water SCHEMBL16395781 | 0.98 | EPHX2 (0.43) | EPHX2CA2CA1EPHX1PPARA | |
| Water SCHEMBL6242366 | 0.98 | EPHX2 (0.43) | EPHX2CA2CA1EPHX1PPARA | |
| Water SCHEMBL16395987 | 0.95 | EPHX2 (0.47) | EPHX2CA2CA1EPHX1PPARA | |
| SCHEMBL10232056 | 0.93 | EPHX2 (0.40) | EPHX2CA2CA1EPHX1PPARA | |
| SCHEMBL8504724 | 0.90 | EPHX2 (0.43) | EPHX2CA2CA1EPHX1PPARA | |
| SCHEMBL11505829 | 0.88 | EPHX2 (0.42) | EPHX2CA2CA1EPHX1S1PR1 | |
| SCHEMBL11504761 | 0.88 | EPHX2 (0.42) | EPHX2CA2CA1EPHX1S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1532168-B1 | METHOD FOR REFOLDING NEISSERIAL NSPA PROTEIN | GLAXOSMITHKLINE BIOLOG SA (BE) | 2014-07-23 | — | — | EP | claimed |
| JP-4652808-B2 | — | — | 2011-03-16 | — | — | JP | claimed |
| US-20100291137-A1 | METHOD FOR REFOLDING NEISSERIAL NSPA PROTEIN | GLAXOSMITHKLINE BIOLOGICALS SA (BE) | 2010-11-18 | — | — | US | claimed |
| EP-1572729-B1 | MUTANT FRPB PROTEIN AND REFOLDING METHOD | GLAXOSMITHKLINE BIOLOG SA (BE) | 2010-09-22 | — | — | EP | claimed |
| US-20080025993-A1 | Method for Refolding Neisserial Nspa Protein | GLAXOSMITHKLINE BIOLOGICALS SA (BE) | 2008-01-31 | — | — | US | claimed |
| US-20060141563-A1 | Mutant protein and refolding method | GLAXOSMITHKLINE BIOLOGICALS S.A. (BE) | 2006-06-29 | — | — | US | claimed |
| JP-2006511463-A | — | — | 2006-04-06 | — | — | JP | claimed |
| EP-1572729-A2 | MUTANT PROTEIN AND REFOLDING METHOD | GlaxoSmithKline Biologicals S.A. (BE) | 2005-09-14 | — | — | EP | claimed |
| EP-1532168-A2 | METHOD FOR REFOLDING NEISSERIAL NSPA PROTEIN | GlaxoSmithKline Biologicals S.A. (BE) | 2005-05-25 | — | — | EP | claimed |
| WO-2004020463-A2 | MUTANT PROTEIN AND REFOLDING METHOD | GLAXOSMITHKLINE BIOLOGICALS SA (BE) | 2004-03-11 | — | — | WO | claimed |
| WO-2004020452-A2 | METHOD FOR REFOLDING NEISSERIAL NSPA PROTEIN | GLAXOSMITHKLINE BIOLOGICALS SA (BE) | 2004-03-11 | — | — | WO | claimed |
| US-5900386-A | GROUP IB OR 8 METALS ON SUPPORT | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1999-05-04 | — | — | US | claimed |
| EP-0841566-A1 | Positive control plasma for lupus anticoagulant | Pentapharm A.G. (CH) | 1998-05-13 | — | — | EP | claimed |
| EP-1532168-B1 | METHOD FOR REFOLDING NEISSERIAL NSPA PROTEIN | GLAXOSMITHKLINE BIOLOG SA (BE) | 2014-07-23 | — | — | EP | disclosed |
| US-20100291137-A1 | METHOD FOR REFOLDING NEISSERIAL NSPA PROTEIN | GLAXOSMITHKLINE BIOLOGICALS SA (BE) | 2010-11-18 | — | — | US | disclosed |
| EP-1572729-B1 | MUTANT FRPB PROTEIN AND REFOLDING METHOD | GLAXOSMITHKLINE BIOLOG SA (BE) | 2010-09-22 | — | — | EP | disclosed |
| US-5620584-A | Electrochemical reduction of metal salts as a method of preparing highly dispersed metal colloids and substrate fixed metal clusters by electrochemical reduction of metal salts | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 1997-04-15 | — | — | US | disclosed |
| WO-1997012952-A1 | LAUNDRY DETERGENT COMPOSITION | UNILEVER PLC (GB) | 1997-04-10 | — | — | WO | disclosed |
| EP-0672765-A1 | Electrochemical reduction of metal salts as a method of preparing highly dispersed metal colloids and substrate fixed metal clusters by electrochemical reduction of metal salts | Studiengesellschaft Kohle mbH (DE) | 1995-09-20 | — | — | EP | disclosed |
| US-5403505-A | An antiseptic concentrate solution comprising a polyamides or polyamideether copolymers, a quaternary ammonium, a phenol, a biguanide and a quaternary phosphonium compounds; stability, water solubility; microbiocides | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1995-04-04 | — | — | US | disclosed |