Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 19/20 | 0.55 |
| ▸ | ROS1 | P08922 | 1/20 | 0.42 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26402655 | 0.93 | EGFR (0.49) | EGFRROS1ALK | |
| SCHEMBL26383298 | 0.93 | EGFR (0.57) | EGFRALK | |
| SCHEMBL26398839 | 0.90 | ALK (0.46) | EGFRROS1ALK | |
| SCHEMBL26388116 | 0.90 | EGFR (0.57) | EGFRROS1ALK | |
| SCHEMBL26388363 | 0.90 | EGFR (0.59) | EGFR | |
| SCHEMBL26385707 | 0.89 | EGFR (0.56) | EGFRALK | |
| SCHEMBL26379853 | 0.88 | EGFR (0.56) | EGFRROS1ALK | |
| SCHEMBL26378824 | 0.87 | EGFR (0.57) | EGFRROS1ALK | |
| SCHEMBL26379828 | 0.86 | EGFR (0.57) | EGFRROS1ALK | |
| SCHEMBL26396005 | 0.86 | EGFR (0.75) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230310428-A1 | EGFR INHIBITOR AND PREPARATION METHOD AND USE THEREOF | Hongyun Biotech Co., Ltd. (CN) | 2023-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230310428-A1 | EGFR INHIBITOR AND PREPARATION METHOD AND USE THEREOF | EGFR, ERBB2, ERBB4 | EGFR 1/4885ROS1 41/4885ALK 58/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.