SCHEMBL2639167

SCHEMBL2639167

N#CCCCNN

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11907666 0.92
SCHEMBL53945 0.81
SCHEMBL1707503 0.75 TSHR (0.45)
SCHEMBL11139184 0.73 TSHR (0.43)
SCHEMBL11140684 0.73 TSHR (0.43)
SCHEMBL23696207 0.71
SCHEMBL12060453 0.71
SCHEMBL14316348 0.71
SCHEMBL10695182 0.71
SCHEMBL97294 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0740654-B1 MONOAMINE OXIDASE B INHIBITORS, PROCESSES FOR THEIR PREPARATION AND USE THEREOF MAYOLY SPINDLER LAB (FR) 1999-10-13 EP claimed
US-5811456-A TREATMENT OF ALZHEIMER'S DISEASE LABORATOIRES MAYOLY SPINDLER (FR) 1998-09-22 US claimed
JP-H09507673-A 1997-08-05 JP claimed
EP-0740654-A1 MONOAMINE OXIDASE B INHIBITORS, PROCESSES FOR THEIR PREPARATION AND USE THEREOF LABORATOIRES MAYOLY SPINDLER (FR) 1996-11-06 EP claimed
WO-1995019960-A1 MONOAMINE OXIDASE B INHIBITORS, PROCESSES FOR THEIR PREPARATION AND USE THEREOF LABORATOIRES MAYOLY SPINDLER (FR) 1995-07-27 WO claimed
EP-3512604-B1 STABLE YELLOW IMIDAZOLIUM COMPOUNDS AND METHODS FOR THEIR USE WELLA OPERATIONS US LLC (US) 2023-05-31 EP disclosed
US-10093807-B2 Stable yellow imidazolium compounds NOXELL CORPORATION (US) 2018-10-09 US disclosed
US-20180141898-A1 PESTICIDALLY ACTIVE OXIME AND HYDRAZONE DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2018-05-24 US disclosed
US-20180078477-A1 Method of Coloring Hair with Washfast Yellow Imidazolium Direct Dye Compounds WELLA OPERATIONS US, LLC 2018-03-22 US disclosed
US-20180079907-A1 Stable Yellow Imidazolium Compounds WELLA OPERATIONS US, LLC 2018-03-22 US disclosed
US-9918919-B1 Method of coloring hair with washfast yellow imidazolium direct dye compounds NOXELL CORPORATION (US) 2018-03-20 US disclosed
EP-2195029-A2 TREATMENT AND PREVENTION OF NEURODEGENERATIVE DISEASES Oryzon Genomics SA (ES) 2010-06-16 EP disclosed
WO-2009027349-A2 TREATMENT AND PREVENTION OF NEURODEGENERATIVE DISEASES ORYZON GENOMICS SA (ES) 2009-03-05 WO disclosed
EP-0740654-B1 MONOAMINE OXIDASE B INHIBITORS, PROCESSES FOR THEIR PREPARATION AND USE THEREOF MAYOLY SPINDLER LAB (FR) 1999-10-13 EP disclosed
US-5811456-A TREATMENT OF ALZHEIMER'S DISEASE LABORATOIRES MAYOLY SPINDLER (FR) 1998-09-22 US disclosed
EP-0740654-A1 MONOAMINE OXIDASE B INHIBITORS, PROCESSES FOR THEIR PREPARATION AND USE THEREOF LABORATOIRES MAYOLY SPINDLER (FR) 1996-11-06 EP disclosed
WO-1995019960-A1 MONOAMINE OXIDASE B INHIBITORS, PROCESSES FOR THEIR PREPARATION AND USE THEREOF LABORATOIRES MAYOLY SPINDLER (FR) 1995-07-27 WO disclosed