Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 14/20 | 0.52 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.41 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.35 |
| ▸ | GBA1 | P04062 | 2/20 | 0.35 |
| ▸ | LCT | P09848 | 2/20 | 0.35 |
| ▸ | UGCG | Q16739 | 2/20 | 0.35 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2638911 | 0.91 | S1PR1 (0.52) | S1PR1S1PR3PDCD1CD274GBA1 | |
| SCHEMBL2433683 | 0.85 | S1PR1 (0.70) | S1PR1S1PR3 | |
| SCHEMBL1566861 | 0.83 | S1PR1 (0.75) | S1PR1S1PR3 | |
| SCHEMBL1566860 | 0.83 | S1PR1 (0.75) | S1PR1S1PR3 | |
| SCHEMBL12631640 | 0.83 | S1PR1 (0.75) | S1PR1S1PR3 | |
| SCHEMBL4664311 | 0.81 | S1PR1 (0.46) | S1PR1S1PR3GBA1LCTUGCG | |
| SCHEMBL2638704 | 0.81 | S1PR1 (0.51) | S1PR1S1PR3PDCD1CD274RORC | |
| SCHEMBL4664536 | 0.79 | S1PR1 (0.71) | S1PR1S1PR3 | |
| SCHEMBL2639815 | 0.78 | S1PR1 (0.73) | S1PR1S1PR3 | |
| SCHEMBL27876684 | 0.77 | S1PR1 (0.50) | S1PR1S1PR3PDCD1CD274RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4700616-B2 | — | — | 2011-06-15 | — | — | JP | claimed |
| EP-1633336-A4 | IMMUNOSUPPRESSANT COMPOUNDS AND COMPOSITIONS | IRM LLC (BM) | 2008-10-29 | — | — | EP | claimed |
| EP-1633336-A2 | IMMUNOSUPPRESSANT COMPOUNDS AND COMPOSITIONS | IRM LLC (BM) | 2006-03-15 | — | — | EP | claimed |
| WO-2004103306-A2 | IMMUNOSUPPRESSANT COMPOUNDS AND COMPOSITIONS | IRM LLC (BM) | 2004-12-02 | — | — | WO | claimed |
| EP-1633336-A4 | IMMUNOSUPPRESSANT COMPOUNDS AND COMPOSITIONS | IRM LLC (BM) | 2008-10-29 | — | — | EP | disclosed |
| EP-1633336-A2 | IMMUNOSUPPRESSANT COMPOUNDS AND COMPOSITIONS | IRM LLC (BM) | 2006-03-15 | — | — | EP | disclosed |
| WO-2004103306-A2 | IMMUNOSUPPRESSANT COMPOUNDS AND COMPOSITIONS | IRM LLC (BM) | 2004-12-02 | — | — | WO | disclosed |