Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 11/20 | 0.54 |
| ▸ | GSK3A | P49840 | 10/20 | 0.54 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.49 |
| ▸ | WNT1 | P04628 | 2/20 | 0.49 |
| ▸ | ABL1 | P00519 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | AAK1 | Q2M2I8 | 4/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.45 |
| ▸ | PIM1 | P11309 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31243443 | 0.91 | GSK3A (0.46) | GSK3BGSK3ADYRK1AWNT1ABL1 | |
| SCHEMBL26129273 | 0.91 | GSK3A (0.46) | GSK3BGSK3ADYRK1AWNT1ABL1 | |
| SCHEMBL26395369 | 0.89 | GSK3B (0.55) | GSK3BGSK3ADYRK1AWNT1ABL1 | |
| Hydrochloric Acid SCHEMBL26131872 | 0.88 | GSK3B (0.54) | GSK3BGSK3ADYRK1AWNT1ABL1 | |
| SCHEMBL26394722 | 0.88 | GSK3A (0.63) | GSK3BGSK3ADYRK1AWNT1AAK1 | |
| SCHEMBL26395355 | 0.87 | GSK3A (0.53) | GSK3BGSK3ADYRK1AWNT1AAK1 | |
| Hydrochloric Acid SCHEMBL31243420 | 0.87 | GSK3A (0.62) | GSK3BGSK3ADYRK1AWNT1AAK1 | |
| SCHEMBL26394693 | 0.87 | GSK3B (0.57) | GSK3BGSK3ADYRK1AWNT1AAK1 | |
| Hydrochloric Acid SCHEMBL26130533 | 0.87 | GSK3A (0.62) | GSK3BGSK3ADYRK1AWNT1AAK1 | |
| SCHEMBL26394423 | 0.87 | GSK3B (0.57) | GSK3BGSK3ADYRK1AWNT1AAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023186773-A1 | SUBSTITUTED 3-AMINO INDAZOLE DERIVATIVES AS KINASE INHIBITORS | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2023-10-05 | — | — | WO | disclosed |