Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 8/20 | 0.55 |
| ▸ | GSK3A | P49840 | 7/20 | 0.55 |
| ▸ | AAK1 | Q2M2I8 | 8/20 | 0.51 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.49 |
| ▸ | GAK | O14976 | 1/20 | 0.48 |
| ▸ | STK16 | O75716 | 1/20 | 0.48 |
| ▸ | BMP2K | Q9NSY1 | 1/20 | 0.48 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL26132787 | 0.99 | GSK3B (0.55) | GSK3BGSK3AAAK1DYRK1AGAK | |
| Hydrochloric Acid SCHEMBL31243428 | 0.99 | GSK3B (0.55) | GSK3BGSK3AAAK1DYRK1AGAK | |
| SCHEMBL26394863 | 0.91 | GSK3B (0.53) | GSK3BGSK3AAAK1DYRK1A | |
| Hydrochloric Acid SCHEMBL26130882 | 0.90 | GSK3B (0.52) | GSK3BGSK3AAAK1DYRK1A | |
| SCHEMBL26394920 | 0.87 | GSK3B (0.48) | GSK3BGSK3AAAK1DYRK1A | |
| SCHEMBL26394532 | 0.87 | GSK3A (0.68) | GSK3BGSK3AAAK1DYRK1A | |
| Hydrochloric Acid SCHEMBL26130611 | 0.87 | GSK3B (0.47) | GSK3BGSK3AAAK1DYRK1A | |
| SCHEMBL26395004 | 0.87 | GSK3B (0.47) | GSK3BGSK3AAAK1DYRK1A | |
| Hydrochloric Acid SCHEMBL31243411 | 0.86 | GSK3A (0.67) | GSK3BGSK3AAAK1DYRK1A | |
| Hydrochloric Acid SCHEMBL26131892 | 0.86 | GSK3A (0.67) | GSK3BGSK3AAAK1DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023186773-A1 | SUBSTITUTED 3-AMINO INDAZOLE DERIVATIVES AS KINASE INHIBITORS | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2023-10-05 | — | — | WO | disclosed |