Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 6/20 | 0.55 |
| ▸ | GSK3B | P49841 | 9/20 | 0.48 |
| ▸ | GSK3A | P49840 | 8/20 | 0.48 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | WNT1 | P04628 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL31243719 | 0.94 | AAK1 (0.49) | AAK1GSK3BGSK3ADYRK1AWNT1 | |
| Trifluoroacetic Acid SCHEMBL26130936 | 0.94 | AAK1 (0.49) | AAK1GSK3BGSK3ADYRK1AWNT1 | |
| SCHEMBL26394375 | 0.89 | GSK3B (0.51) | AAK1GSK3BGSK3APIK3CDPIM1 | |
| SCHEMBL26394851 | 0.89 | AAK1 (0.69) | AAK1GSK3BGSK3APIK3CDPIM1 | |
| Hydrochloric Acid SCHEMBL26130354 | 0.88 | GSK3B (0.50) | AAK1GSK3BGSK3APIK3CDPIM1 | |
| SCHEMBL26394429 | 0.88 | GSK3B (0.50) | AAK1GSK3BGSK3APIK3CDPIM1 | |
| Hydrochloric Acid SCHEMBL26128757 | 0.88 | AAK1 (0.67) | AAK1GSK3BGSK3APIK3CDPIM1 | |
| Hydrochloric Acid SCHEMBL26131851 | 0.88 | GSK3B (0.49) | AAK1GSK3BGSK3APIK3CDPIM1 | |
| SCHEMBL26394423 | 0.87 | GSK3B (0.57) | AAK1GSK3BGSK3APIK3CDPIM1 | |
| SCHEMBL26395378 | 0.87 | GSK3B (0.49) | AAK1GSK3BGSK3APIK3CDPIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023186773-A1 | SUBSTITUTED 3-AMINO INDAZOLE DERIVATIVES AS KINASE INHIBITORS | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2023-10-05 | — | — | WO | disclosed |