Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 16/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.41 |
| ▸ | GSK3A | P49840 | 8/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | AGER | Q15109 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 2/20 | 0.39 |
| ▸ | CDK2 | P24941 | 2/20 | 0.39 |
| ▸ | CDC7 | O00311 | 1/20 | 0.39 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | PAK4 | O96013 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.39 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
| ▸ | CLK2 | P49760 | 1/20 | 0.39 |
| ▸ | CDK7 | P50613 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL31243432 | 0.99 | GSK3B (0.41) | GSK3BDYRK1AGSK3AHTR1ACYP1A2 | |
| Hydrochloric Acid SCHEMBL26129767 | 0.99 | GSK3B (0.41) | GSK3BDYRK1AGSK3AHTR1ACYP1A2 | |
| SCHEMBL26396296 | 0.98 | GSK3B (0.41) | GSK3BDYRK1AGSK3AHTR1ACYP1A2 | |
| Hydrochloric Acid SCHEMBL26131801 | 0.97 | GSK3B (0.40) | GSK3BDYRK1AGSK3AHTR1ACYP1A2 | |
| SCHEMBL26396281 | 0.95 | GSK3B (0.42) | GSK3BDYRK1AGSK3ACYP1A2PIM1 | |
| Hydrochloric Acid SCHEMBL26126425 | 0.95 | GSK3B (0.42) | GSK3BDYRK1AGSK3ACYP1A2PIM1 | |
| SCHEMBL26395004 | 0.90 | GSK3B (0.47) | GSK3BDYRK1AGSK3APIM1CDK2 | |
| SCHEMBL26396318 | 0.86 | DYRK1A (0.45) | GSK3BDYRK1AGSK3APIM1CDK2 | |
| SCHEMBL26394149 | 0.85 | GSK3B (0.46) | GSK3BGSK3APIM1CDK2PIK3CD | |
| Hydrochloric Acid SCHEMBL26129160 | 0.85 | DYRK1A (0.44) | GSK3BDYRK1AGSK3APIM1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023186773-A1 | SUBSTITUTED 3-AMINO INDAZOLE DERIVATIVES AS KINASE INHIBITORS | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2023-10-05 | — | — | WO | disclosed |