⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17784004 | 0.78 | — | — | |
| SCHEMBL7851121 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL9792877 | 0.73 | — | — | |
| SCHEMBL1289462 | 0.72 | — | — | |
| SCHEMBL1064822 | 0.72 | — | — | |
| SCHEMBL8935565 | 0.72 | — | — | |
| SCHEMBL161563 | 0.72 | — | — | |
| SCHEMBL6036511 | 0.69 | — | — | |
| SCHEMBL1896988 | 0.69 | — | — | |
| SCHEMBL21280807 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113840828-B | Process for preparing GalNAc phosphoramidite epimer | 豪夫迈·罗氏有限公司 | 2024-01-16 | — | — | CN | claimed |
| CN-117362336-A | Purification method and preparation method of diamine phosphite compound | 天津兴博润生物制药有限公司 | 2024-01-09 | — | — | CN | claimed |
| CN-113840828-A | Process for the preparation of GalNAc phosphoramidite epimers | 豪夫迈·罗氏有限公司 | 2021-12-24 | — | — | CN | claimed |
| CN-111233920-A | Simple purification method of phosphorus-containing protective agent | 上海索绿新材料有限公司 | 2020-06-05 | — | — | CN | claimed |
| CN-109810141-A | Sulfur-bearing phosphorous imide ester, preparation method and its application | 中国石油大学(华东) | 2019-05-28 | — | — | CN | claimed |
| JP-4796576-B2 | — | — | 2011-10-19 | — | — | JP | claimed |
| CN-102212065-A | Isonucleoside compound or ortho-phosphite derivative thereof and preparation method and application thereof | UNIV BEIJING | 2011-10-12 | — | — | CN | claimed |
| EP-1765845-B1 | STABLE CYANINE DYE PHOSPHORAMIDITES | BECKMAN COULTER INC (US) | 2010-10-27 | — | — | EP | claimed |
| US-7230117-B2 | Stable cyanine dye phosphoramidites | BECKMAN COULTER, INC. (US) | 2007-06-12 | — | — | US | claimed |
| EP-1765845-A1 | STABLE CYANINE DYE PHOSPHORAMIDITES | Beckman Coulter, Inc. (US) | 2007-03-28 | — | — | EP | claimed |
| WO-2006017196-A1 | STABLE CYANINE DYE PHOSPHORAMIDITES | BECKMAN COULTER, INC. (US) | 2006-02-16 | — | — | WO | claimed |
| US-20060009624-A1 | Phosphoramidites of substituted cyclic (cyclopentene, cyclohexene, and cyclohepene) bridged cyanine dyes, particularly those containing a N,N-diisopropyl-O- beta -cyanoethyl phosphoramidite group; preparation and use in labeling oligonucleotides, proteins and peptides | BECKMAN COULTER, INC. | 2006-01-12 | — | — | US | claimed |
| WO-2024081851-A2 | PHOSPHORAMIDITE CONJUGATES AND METHODS OF FORMING SYNTHETIC OLIGONUCLEOTIDES THEREFROM | CARNEGIE MELLON UNIVERSITY (US) | 2024-04-18 | — | — | WO | disclosed |
| CN-113840828-B | Process for preparing GalNAc phosphoramidite epimer | 豪夫迈·罗氏有限公司 | 2024-01-16 | — | — | CN | disclosed |
| CN-117362336-A | Purification method and preparation method of diamine phosphite compound | 天津兴博润生物制药有限公司 | 2024-01-09 | — | — | CN | disclosed |
| CN-114516896-A | Artificial deoxyribose with hypoxia microenvironment response and application thereof | 上海交通大学医学院附属仁济医院 | 2022-05-20 | — | — | CN | disclosed |
| CN-1347418-A | Novel nucleosides and oligonucleotide analogues | SANKYO CO (JP) | 2002-05-01 | — | — | CN | disclosed |
| EP-0886638-A4 | IMPROVED PROCESS FOR THE SYNTHESIS OF OLIGOMERIC COMPOUNDS | ISIS PHARMACEUTICALS INC (US) | 2000-12-27 | — | — | EP | disclosed |
| EP-0886638-A1 | IMPROVED PROCESS FOR THE SYNTHESIS OF OLIGOMERIC COMPOUNDS | ISIS PHARMACEUTICALS, INC. (US) | 1998-12-30 | — | — | EP | disclosed |
| WO-1997019092-A1 | IMPROVED PROCESS FOR THE SYNTHESIS OF OLIGOMERIC COMPOUNDS | ISIS PHARMACEUTICALS, INC. (US) | 1997-05-29 | — | — | WO | disclosed |