Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 19/20 | 0.65 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.63 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.63 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.44 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | CDK9 | P50750 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2640126 | 0.84 | PDPK1 (0.69) | PDPK1PIK3CAPIK3CGCCNT1CCNA2 | |
| SCHEMBL14001685 | 0.81 | PDPK1 (0.78) | PDPK1PIK3CAPIK3CG | |
| SCHEMBL1456749 | 0.80 | PDPK1 (0.64) | PDPK1PIK3CAPIK3CG | |
| SCHEMBL1604109 | 0.79 | PDPK1 (1.00) | PDPK1PIK3CAPIK3CG | |
| SCHEMBL13541693 | 0.79 | PDPK1 (0.74) | PDPK1PIK3CAPIK3CG | |
| SCHEMBL1603822 | 0.78 | PDPK1 (0.70) | PDPK1PIK3CAPIK3CGCCNT1CCNA2 | |
| SCHEMBL1604236 | 0.78 | PDPK1 (1.00) | PDPK1PIK3CAPIK3CGCCNT1CCNA2 | |
| SCHEMBL1604708 | 0.78 | PDPK1 (1.00) | PDPK1PIK3CAPIK3CGCCNT1CCNA2 | |
| SCHEMBL1603767 | 0.78 | PDPK1 (1.00) | PDPK1PIK3CAPIK3CGCCNT1CCNA2 | |
| SCHEMBL1456782 | 0.77 | PDPK1 (0.61) | PDPK1PIK3CAPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2011526260-A | — | — | 2011-10-06 | — | — | JP | claimed |
| WO-2010000364-A1 | PYRROLOPYRIDINYLPYRIMIDIN-2-YLAMINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2010-01-07 | — | — | WO | claimed |