Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 6/20 | 0.67 |
| ▸ | CES2 | O00748 | 5/20 | 0.67 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.50 |
| ▸ | GPR84 | Q9NQS5 | 6/20 | 0.48 |
| ▸ | PPARG | P37231 | 6/20 | 0.48 |
| ▸ | PPARD | Q03181 | 6/20 | 0.48 |
| ▸ | PPARA | Q07869 | 6/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TLR2 | O60603 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | FABP4 | P15090 | 2/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.48 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.48 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11942792 | 0.98 | CES1 (0.68) | CES1CES2GPR84PPARGPPARD | |
| SCHEMBL8822874 | 0.98 | CES1 (0.68) | CES1CES2GPR84PPARGPPARD | |
| SCHEMBL13171261 | 0.98 | CES1 (0.68) | CES1CES2GPR84PPARGPPARD | |
| SCHEMBL12198772 | 0.98 | CES1 (0.68) | CES1CES2GPR84PPARGPPARD | |
| SCHEMBL13941288 | 0.98 | CES1 (0.68) | CES1CES2GPR84PPARGPPARD | |
| SCHEMBL12198774 | 0.98 | CES1 (0.68) | CES1CES2GPR84PPARGPPARD | |
| SCHEMBL12198779 | 0.98 | CES1 (0.68) | CES1CES2GPR84PPARGPPARD | |
| SCHEMBL8758526 | 0.98 | CES1 (0.68) | CES1CES2GPR84PPARGPPARD | |
| SCHEMBL11152095 | 0.98 | CES1 (0.68) | CES1CES2GPR84PPARGPPARD | |
| SCHEMBL26754674 | 0.98 | CES1 (0.68) | CES1CES2GPR84PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049120-A1 | UROTENSIN II RECEPTOR ANTAGONISTS | Janssen Pharmaceutica, N.V. (BE) | 2009-04-22 | — | — | EP | claimed |
| WO-2008016534-A1 | UROTENSIN II RECEPTOR ANTAGONISTS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2008-02-07 | — | — | WO | claimed |
| EP-0061689-B1 | RADIATION SENSITIVE POLYMER MATERIALS | Hitachi, Ltd. (JP) | 1986-08-27 | — | — | EP | claimed |
| EP-2438070-A1 | GLYCINE B ANTAGONISTS | Merz Pharma GmbH & Co. KGaA (DE) | 2012-04-11 | — | — | EP | disclosed |
| WO-2010139483-A1 | GLYCINE B ANTAGONISTS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2010-12-09 | — | — | WO | disclosed |
| EP-2049120-A1 | UROTENSIN II RECEPTOR ANTAGONISTS | Janssen Pharmaceutica, N.V. (BE) | 2009-04-22 | — | — | EP | disclosed |
| WO-2008016534-A1 | UROTENSIN II RECEPTOR ANTAGONISTS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2008-02-07 | — | — | WO | disclosed |
| EP-0061689-B1 | RADIATION SENSITIVE POLYMER MATERIALS | Hitachi, Ltd. (JP) | 1986-08-27 | — | — | EP | disclosed |
| US-4172731-A | Photographic element containing a light absorbing matting agent | EASTMAN KODAK COMPANY (US) | 1979-10-30 | — | — | US | disclosed |