Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CACNA1H | O95180 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.38 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26408046 | 0.96 | CACNA1H (0.46) | GRM4MEN1KMT2ACACNA1HSMN1; SMN2 | |
| SCHEMBL26082303 | 0.91 | GRM4 (0.42) | GRM4MEN1KMT2ACACNA1HSMN1; SMN2 | |
| SCHEMBL26082304 | 0.89 | SMN1; SMN2 (0.46) | GRM4MEN1KMT2ACACNA1HSMN1; SMN2 | |
| SCHEMBL26409932 | 0.88 | CACNA1H (0.36) | GRM4MEN1KMT2ACACNA1HCACNA1G | |
| SCHEMBL26408958 | 0.87 | GRM4 (0.41) | GRM4MEN1KMT2ACACNA1HSMN1; SMN2 | |
| SCHEMBL26408044 | 0.86 | CACNA1H (0.48) | GRM4MEN1KMT2ACACNA1HSMN1; SMN2 | |
| SCHEMBL26409917 | 0.86 | GRM4 (0.47) | GRM4MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL26409922 | 0.86 | CACNA1H (0.48) | GRM4MEN1KMT2ACACNA1HSMN1; SMN2 | |
| SCHEMBL30546530 | 0.83 | CACNA1H (0.41) | GRM4MEN1KMT2ACACNA1HSMN1; SMN2 | |
| SCHEMBL26411382 | 0.83 | GRM4 (0.40) | GRM4MEN1KMT2ACACNA1HSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192675-A1 | T-TYPE CALCIUM CHANNEL MODULATORS COMPRISING AN AZASPIRONONANE CORE AND METHODS OF USE THEREOF | PRAXIS PRECISION MEDICINES, INC. (US) | 2023-10-05 | — | — | WO | disclosed |