Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 18/20 | 0.63 |
| ▸ | HDAC3 | O15379 | 10/20 | 0.63 |
| ▸ | HDAC2 | Q92769 | 9/20 | 0.63 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.63 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.63 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.63 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.63 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.63 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.63 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.63 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.63 |
| ▸ | NCOR2 | Q9Y618 | 5/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL673704 | 0.80 | HDAC1 (0.60) | HDAC1HDAC3HDAC2HDAC4HDAC7 | |
| SCHEMBL673705 | 0.77 | HDAC1 (1.00) | HDAC1HDAC3HDAC2HDAC4HDAC7 | |
| SCHEMBL24119315 | 0.76 | HDAC1 (0.71) | HDAC1HDAC3HDAC2HDAC4HDAC7 | |
| SCHEMBL11719473 | 0.75 | HDAC3 (0.72) | HDAC1HDAC3HDAC2HDAC4HDAC7 | |
| SCHEMBL13110778 | 0.75 | HDAC1 (0.64) | HDAC1HDAC3HDAC2HDAC4HDAC7 | |
| SCHEMBL8401704 | 0.75 | HDAC1 (0.89) | HDAC1HDAC3HDAC2HDAC4HDAC7 | |
| SCHEMBL27406949 | 0.74 | HDAC1 (0.69) | HDAC1HDAC3HDAC2HDAC4HDAC7 | |
| SCHEMBL27406946 | 0.74 | HDAC1 (0.69) | HDAC1HDAC3HDAC2HDAC4HDAC7 | |
| SCHEMBL6077125 | 0.74 | HDAC1 (0.58) | HDAC1HDAC3HDAC2HDAC4HDAC7 | |
| SCHEMBL23059530 | 0.74 | HDAC3 (0.62) | HDAC1HDAC3HDAC2HDAC4HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011143314-A1 | COMPOSITIONS AND METHODS FOR REDUCING PROLIFERATION AND VIABILITY OF LYMPHOBLASTOID CELLS | ARNO THERAPEUTICS, INC (US) | 2011-11-17 | — | — | WO | disclosed |