Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 12/20 | 0.48 |
| ▸ | ALK | Q9UM73 | 4/20 | 0.46 |
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2641691 | 1.00 | PTK2 (0.48) | PTK2ALKLRRK2 | |
| SCHEMBL14767942 | 1.00 | PTK2 (0.48) | PTK2ALKLRRK2 | |
| SCHEMBL15226744 | 0.94 | PTK2 (0.47) | PTK2ALKLRRK2 | |
| SCHEMBL15226750 | 0.94 | PTK2 (0.47) | PTK2ALKLRRK2 | |
| SCHEMBL15226870 | 0.94 | PTK2 (0.48) | PTK2ALKLRRK2 | |
| SCHEMBL2036291 | 0.94 | PTK2 (0.48) | PTK2ALKLRRK2 | |
| SCHEMBL2033944 | 0.94 | PTK2 (0.48) | PTK2ALKLRRK2 | |
| SCHEMBL15226868 | 0.94 | PTK2 (0.48) | PTK2ALKLRRK2 | |
| SCHEMBL14767937 | 0.93 | PTK2 (0.49) | PTK2ALKLRRK2 | |
| SCHEMBL2641694 | 0.93 | PTK2 (0.49) | PTK2ALKLRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8399433-B2 | Amino pyrimidine anticancer compounds | OSI Pharmaceuticals, LLC (US) | 2013-03-19 | — | — | US | disclosed |
| EP-2438056-A2 | AMINO PYRIMIDINE ANTICANCER COMPOUNDS | OSI Pharmaceuticals, LLC (US) | 2012-04-11 | — | — | EP | disclosed |
| WO-2010141406-A2 | AMINO PYRIMIDINE ANTICANCER COMPOUNDS | OSI PHARMACEUTICALS, INC. (US) | 2010-12-09 | — | — | WO | disclosed |