Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | RELA | Q04206 | 5/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | DHFR | P00374 | 1/20 | 0.48 |
| ▸ | APP | P05067 | 4/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.47 |
| ▸ | ESR1 | P03372 | 2/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2641784 | 1.00 | MAPT (0.56) | MAPTTRPA1NPC1RAB9AMEN1 | |
| SCHEMBL4536873 | 0.84 | MEN1 (0.58) | NPC1MEN1KMT2ARELACYP1A2 | |
| SCHEMBL4536867 | 0.84 | MEN1 (0.58) | NPC1MEN1KMT2ARELACYP1A2 | |
| SCHEMBL5864850 | 0.81 | GRM4 (0.65) | MAPTTRPA1NPC1RAB9ARELA | |
| SCHEMBL5864846 | 0.81 | GRM4 (0.65) | MAPTTRPA1NPC1RAB9ARELA | |
| Hydrochloric Acid SCHEMBL5865178 | 0.79 | GRM4 (0.63) | MAPTTRPA1NPC1RAB9ARELA | |
| Hydrochloric Acid SCHEMBL5865175 | 0.79 | GRM4 (0.63) | MAPTTRPA1NPC1RAB9ARELA | |
| SCHEMBL4542155 | 0.79 | GRM4 (0.61) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL4542158 | 0.79 | GRM4 (0.61) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL5864866 | 0.78 | MAPT (0.53) | MAPTTRPA1NPC1RAB9ARELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011141515-A1 | DIAGNOSTIC AGENTS FOR AMYLOID BETA IMAGING | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2011-11-17 | — | — | WO | claimed |
| WO-2011141515-A1 | DIAGNOSTIC AGENTS FOR AMYLOID BETA IMAGING | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2011-11-17 | — | — | WO | disclosed |