Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 18/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | SNCA | P37840 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.53 |
| ▸ | MAT2A | P31153 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2641811 | 1.00 | APP (0.54) | APPMAPTSNCAKCNH2MAT2A | |
| SCHEMBL16502107 | 0.80 | APP (0.53) | APPMAPTSNCAKCNH2 | |
| SCHEMBL17681057 | 0.79 | APP (0.61) | APPMAPTSNCAKCNH2 | |
| SCHEMBL360559 | 0.78 | — | — | |
| SCHEMBL9680312 | 0.78 | APP (0.77) | APPKCNH2MAT2A | |
| SCHEMBL900823 | 0.78 | APP (0.77) | APPKCNH2MAT2A | |
| SCHEMBL19003408 | 0.78 | APP (0.77) | APPKCNH2MAT2A | |
| SCHEMBL9678907 | 0.78 | APP (0.77) | APPKCNH2MAT2A | |
| Hydrochloric Acid SCHEMBL28466493 | 0.77 | KCNQ3 (0.41) | APP | |
| SCHEMBL2641860 | 0.76 | KCNH2 (0.50) | APPMAPTSNCAKCNH2MAT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011141515-A1 | DIAGNOSTIC AGENTS FOR AMYLOID BETA IMAGING | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2011-11-17 | — | — | WO | disclosed |