Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERBB2 | P04626 | 15/20 | 0.69 |
| ▸ | EGFR | P00533 | 6/20 | 0.69 |
| ▸ | BRAF | P15056 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23750174 | 0.93 | ERBB2 (0.79) | ERBB2EGFRBRAF | |
| SCHEMBL30575962 | 0.93 | ERBB2 (0.79) | ERBB2EGFRBRAF | |
| SCHEMBL26418695 | 0.92 | ERBB2 (0.69) | ERBB2EGFRBRAF | |
| SCHEMBL23750119 | 0.92 | ERBB2 (0.69) | ERBB2EGFRBRAF | |
| SCHEMBL23750120 | 0.92 | ERBB2 (0.69) | ERBB2EGFRBRAF | |
| SCHEMBL23750249 | 0.92 | ERBB2 (0.61) | ERBB2EGFRBRAF | |
| SCHEMBL26418691 | 0.90 | ERBB2 (0.67) | ERBB2EGFRBRAF | |
| SCHEMBL23750322 | 0.90 | ERBB2 (0.60) | ERBB2EGFRBRAF | |
| SCHEMBL23750180 | 0.89 | ERBB2 (0.61) | ERBB2EGFRBRAF | |
| SCHEMBL23750169 | 0.86 | ERBB2 (0.61) | ERBB2EGFRBRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230126204-A1 | [1,3]DIAZINO[5,4-d]PYRIMIDINES AS HER2 INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2023-04-27 | — | — | US | disclosed |
| US-20230126204-A1 | [1,3]DIAZINO[5,4-d]PYRIMIDINES AS HER2 INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2023-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230126204-A1 | [1,3]DIAZINO[5,4-d]PYRIMIDINES AS HER2 INHIBITORS | ERBB2, ERBB3, ERBB4 | ERBB2 1/4885EGFR 4/4885BRAF 64/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.