Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | CASP1 | P29466 | 2/20 | 0.61 |
| ▸ | HBB | P68871 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | S100A4 | P26447 | 1/20 | 0.49 |
| ▸ | APP | P05067 | 7/20 | 0.49 |
| ▸ | NQO2 | P16083 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ALPG | P10696 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2641921 | 1.00 | MAPT (0.61) | MAPTMEN1KMT2ASMN1; SMN2CASP1 | |
| SCHEMBL29905719 | 0.83 | MAPT (0.65) | MAPTMEN1KMT2ASMN1; SMN2CASP1 | |
| SCHEMBL2641910 | 0.82 | MAPT (0.41) | MAPTMEN1KMT2ASMN1; SMN2CASP1 | |
| SCHEMBL27898404 | 0.81 | MAPT (0.62) | MAPTMEN1KMT2ASMN1; SMN2CASP1 | |
| SCHEMBL27790862 | 0.81 | MAPT (0.62) | MAPTMEN1KMT2ASMN1; SMN2CASP1 | |
| SCHEMBL2641794 | 0.80 | MAPT (0.61) | MAPTMEN1KMT2ASMN1; SMN2CASP1 | |
| SCHEMBL12186016 | 0.80 | MAPT (0.61) | MAPTMEN1KMT2ASMN1; SMN2CASP1 | |
| SCHEMBL2641897 | 0.80 | MAPT (0.61) | MAPTMEN1KMT2ASMN1; SMN2CASP1 | |
| SCHEMBL2641892 | 0.80 | MAPT (0.61) | MAPTMEN1KMT2ASMN1; SMN2CASP1 | |
| SCHEMBL2641798 | 0.80 | MAPT (0.61) | MAPTMEN1KMT2ASMN1; SMN2CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011141515-A1 | DIAGNOSTIC AGENTS FOR AMYLOID BETA IMAGING | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2011-11-17 | — | — | WO | disclosed |