SCHEMBL26420941

SCHEMBL26420941

c1ccc(-c2ccc(-c3nc(-c4ccccc4)nc(-n4c5ccccc5c5c(-c6ccccc6)c(-c6ccccc6)c6c7ccccc7n(-c7ccccc7)c6c54)n3)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.41
L3MBTL1 Q9Y468 2/20 0.40
ATM Q13315 2/20 0.40
KDM4E B2RXH2 1/20 0.40
AVPR1A P37288 1/20 0.36
IL1R1 P14778 1/20 0.35
MEN1 O00255 4/20 0.35
HTT P42858 2/20 0.35
MAPT P10636 2/20 0.35
ALDH1A1 P00352 2/20 0.35
ABCG2 Q9UNQ0 1/20 0.35
MAPK1 P28482 1/20 0.34
HSP90AA1 P07900 1/20 0.33
NPC1 O15118 1/20 0.33
LMNA P02545 1/20 0.33
RAB9A P51151 1/20 0.33
RXFP1 Q9HBX9 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26420952 1.00 KMT2A (0.41) KMT2AL3MBTL1ATMKDM4EAVPR1A
SCHEMBL24549928 1.00 KMT2A (0.41) KMT2AL3MBTL1ATMKDM4EAVPR1A
SCHEMBL26420953 1.00 KMT2A (0.41) KMT2AL3MBTL1ATMKDM4EAVPR1A
SCHEMBL26420946 0.97 KMT2A (0.38) KMT2AL3MBTL1ATMKDM4EAVPR1A
SCHEMBL26420964 0.97 KMT2A (0.38) KMT2AL3MBTL1ATMKDM4EAVPR1A
SCHEMBL23118902 0.97 KMT2A (0.43) KMT2AL3MBTL1ATMKDM4EIL1R1
SCHEMBL24549531 0.95 KMT2A (0.38) KMT2AL3MBTL1ATMKDM4EAVPR1A
SCHEMBL26420957 0.95 KMT2A (0.38) KMT2AL3MBTL1ATMKDM4EAVPR1A
SCHEMBL26421339 0.95 KMT2A (0.43) KMT2AL3MBTL1ATMKDM4EAVPR1A
SCHEMBL24549687 0.94 KMT2A (0.37) KMT2AL3MBTL1ATMKDM4EAVPR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230128732-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT MATERIAL AND ORGANIC ELECTROLUMINESCENCE ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2023-04-27 US disclosed
US-20230128732-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT MATERIAL AND ORGANIC ELECTROLUMINESCENCE ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2023-04-27 US disclosed