Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 19/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | MITF | O75030 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2643609 | 0.90 | GCK (0.74) | GCKKDM4ENPC1MITFRAB9A | |
| SCHEMBL2643117 | 0.87 | GCK (1.00) | GCKKDM4ENPC1MITFRAB9A | |
| SCHEMBL2642949 | 0.87 | GCK (0.81) | GCKKDM4ENPC1RAB9A | |
| SCHEMBL2642904 | 0.86 | GCK (0.80) | GCKKDM4ENPC1RAB9A | |
| SCHEMBL2643973 | 0.86 | GCK (0.80) | GCKKDM4ENPC1RAB9A | |
| SCHEMBL2642257 | 0.86 | GCK (0.61) | GCKKDM4ENPC1MITFRAB9A | |
| SCHEMBL2643299 | 0.85 | GCK (0.77) | GCK | |
| SCHEMBL2642565 | 0.84 | GCK (0.76) | GCK | |
| SCHEMBL14380059 | 0.84 | GCK (1.00) | GCK | |
| SCHEMBL2643904 | 0.82 | GCK (0.83) | GCKKDM4ENPC1MITFRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1496052-B1 | NOVEL AMINOBENZAMIDE DERIVATIVE | BANYU PHARMA CO LTD (JP) | 2009-08-05 | — | — | EP | disclosed |
| US-7253188-B2 | Aminobenzamide derivative | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2007-08-07 | — | — | US | disclosed |
| US-7253188-B2 | Aminobenzamide derivative | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2007-08-07 | — | — | US | disclosed |
| US-7253188-B2 | Aminobenzamide derivative | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2007-08-07 | — | — | US | disclosed |
| EP-1496052-A1 | NOVEL AMINOBENZAMIDE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2005-01-12 | — | — | EP | disclosed |