Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29599933 | 1.00 | MAPK1 (0.44) | MAPK1TSHRLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL4550172 | 0.89 | MAPK1 (0.45) | MAPK1TSHRLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL3247412 | 0.88 | MAPK1 (0.43) | MAPK1TSHRLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL28811392 | 0.87 | MAPK1 (0.42) | MAPK1TSHRLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL27832441 | 0.86 | MAPK1 (0.41) | MAPK1TSHRLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL31152812 | 0.84 | ATM (0.44) | ALDH1A1TDP1L3MBTL1MAPTATM | |
| SCHEMBL31152809 | 0.84 | ATM (0.44) | ALDH1A1TDP1L3MBTL1MAPTATM | |
| SCHEMBL2610943 | 0.84 | ATM (0.44) | ALDH1A1TDP1L3MBTL1MAPTATM | |
| SCHEMBL28548604 | 0.84 | ABCB1 (0.35) | MAPK1TSHRALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL28376618 | 0.84 | MAPK1 (0.39) | MAPK1TSHRLMNAALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023191533-A1 | THIOBENZIMIDAZOLE DERIVATIVE PREPARATION METHOD AND NOVEL INTERMEDIATE THEREFOR | 고려대학교 산학협력단 | 2023-10-05 | — | — | WO | disclosed |