Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | PDE7A | Q13946 | 8/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.36 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30468965 | 0.78 | TDP1 (0.32) | TDP1TSHRMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL24359523 | 0.78 | TDP1 (0.32) | TDP1TSHRMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL2419394 | 0.77 | PDE7A (0.56) | TDP1TSHRPDE7AMAPK1MAPT | |
| SCHEMBL5859889 | 0.75 | PDE7A (0.50) | TDP1TSHRPDE7AMAPK1MAPT | |
| SCHEMBL11726468 | 0.75 | MAPT (0.52) | TDP1TSHRPDE7AMAPK1MAPT | |
| SCHEMBL11631033 | 0.73 | PDE7A (0.55) | TDP1TSHRPDE7AMAPK1MAPT | |
| SCHEMBL5857819 | 0.73 | PDE7A (0.55) | TDP1TSHRPDE7AMAPK1MAPT | |
| SCHEMBL11653018 | 0.73 | PDE7A (0.63) | TDP1TSHRPDE7AMAPK1MAPT | |
| SCHEMBL5858703 | 0.73 | PDE7A (0.56) | TDP1TSHRPDE7AMAPK1MAPT | |
| SCHEMBL4607929 | 0.73 | PDE7A (0.55) | TDP1TSHRPDE7AMAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118974021-A | Preparation method of thiobenzimidazole derivative and novel intermediate for same | 高丽大学校产学协力团 | 2024-11-15 | — | — | CN | disclosed |
| WO-2023191533-A1 | THIOBENZIMIDAZOLE DERIVATIVE PREPARATION METHOD AND NOVEL INTERMEDIATE THEREFOR | 고려대학교 산학협력단 | 2023-10-05 | — | — | WO | disclosed |
| CN-116348114-A | Thiobenzimidazole derivatives or pharmaceutically acceptable salts thereof and use thereof | 高丽大学校产学协力团 | 2023-06-27 | — | — | CN | disclosed |